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Urinary incontinence and erectile dysfunction are significant adverse outcomes associated with radical prostatectomy in contemporary clinical practice

https://doi.org/10.21886/2308-6424-2025-13-3-91-106

Abstract

In recent years, there has been an increase in the number of newly diagnosed cases of prostate cancer (PCa). Radical prostatectomy (RPE) remains the gold standard treatment for localized forms of the disease. With rapid technological advancements, surgical techniques have evolved from the classical RPE to robot-assisted approaches. However, despite improvements in surgical outcomes and reductions in mortality rates associated with PCa, adverse effects such as urinary incontinence and erectile dysfunction remain significant concerns. These complications substantially impact patients' psycho-emotional well-being, leading to increased levels of anxiety and depression, and often necessitate lifestyle modifications characterized by reduced social and daily activity. This study presents a review and analysis of literature sourced from both domestic and international databases, including the Federal Electronic Medical Library, eLIBRARY, and PubMed. The research focused on current data regarding PCa worldwide, as well as urinary incontinence and erectile dysfunction following RPE, and their effects on the psychological health of patients.

About the Authors

A. I. Bragin-Maltsev
Podgorbunsky Kuzbass Clinical Hospital of Emergency Medical Care; Kemerovo State Medical University
Russian Federation

Andrey I. Bragin-Maltsev

Kemerovo


Competing Interests:

The authors declare no conflict of interest



P. S. Kyzlasov
State Research Center of the Russian Federation — Burnazyan Federal Medical Biophysical Centre of the FMBA of Russia
Russian Federation

Pavel S. Kyzlasov —Dr.Sc.(Med).

Moscow


Competing Interests:

The authors declare no conflict of interest



V. A. Perepechay
Rostov Clinical Hospital — Southern District Medical Centre of the FMBA of Russia; Rostov State Medical University
Russian Federation

Vadim A. Perepechay —Dr.Sc.(Med), Assoc.Prof. (Docent).

Rostov-on-Don


Competing Interests:

The authors declare no conflict of interest



V. N. Pavlov
Bashkir State Medical University
Russian Federation

Valentin N. Pavlov —Dr.Sc.(Med), Full Prof., Acad. of the RAS.

Ufa


Competing Interests:

The authors declare no conflict of interest



R. A. Kazikhinurov
Bashkir State Medical University
Russian Federation

Rustem A. Kazikhinurov — Cand. Sci. (Med.)

Ufa


Competing Interests:

The authors declare no conflict of interest



E. V. Volokitin
Podgorbunsky Kuzbass Clinical Hospital of Emergency Medical Care
Russian Federation

Evgeny E. Volokitin

Kemerovo


Competing Interests:

The authors declare no conflict of interest



A. T. Mustafaev
State Research Center of the Russian Federation — Burnazyan Federal Medical Biophysical Centre of the FMBA of Russia
Russian Federation

Ali T. Mustafayev

Moscow


Competing Interests:

The authors declare no conflict of interest



O. A. Isaev
State Research Center of the Russian Federation — Burnazyan Federal Medical Biophysical Centre of the FMBA of Russia
Russian Federation

Osman A. Isaev

Moscow


Competing Interests:

The authors declare no conflict of interest



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Bragin-Maltsev A.I., Kyzlasov P.S., Perepechay V.A., Pavlov V.N., Kazikhinurov R.A., Volokitin E.V., Mustafaev A.T., Isaev O.A. Urinary incontinence and erectile dysfunction are significant adverse outcomes associated with radical prostatectomy in contemporary clinical practice. Urology Herald. 2025;13(3):91-106. (In Russ.) https://doi.org/10.21886/2308-6424-2025-13-3-91-106

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