Our study included 48 patients who received a first course of Uro-Vaxom in 2007-2008, 19 men with chronic prostatitis/urethroprostatitis, and 29 women with recurrent cystitis. In just five years, it was noted 125 recurrences of urogenital infections, of which 88 cases (70,4%) is required in addition to Uro-Vaxom antibiotics in combination with herbal medicine, and in the remaining 37 cases, and (29,6%), Uro-Vaxom alone was enough to relieve inflammation. In five years there were 254 monthly rate of Uro-Vaxom, of whom 125 (49,2%) with curative intent for recurrent urogenital infections, and 129 (50,8%) – from preventive, without exacerbation of underlying disease. Key for Punishment - intercurrent infection, mainly respiratory (86 cases – 66,7%), stress (14 cases – 10,8%) in the 29 and the cases (22,5%) patients received Uro-Vaxom alone, without a doctor's prescription , focusing on the sensations.

The study included a survey of 42 patients with chronic bacterial prostatitis. Depending on the level of total testosterone, patients were divided into two groups : I group – 20 patients whose serum total testosterone was below the standard ratio (8-12 nmol/l), II group – 22 patients in whom testosterone matched normative range (> 12 nmol/l). The analysis of the study showed that patients with chronic bacterial prostatitis on a background of testosterone deficiency recorded more severe manifestations of infection in the prostate, as revealed by clinical, laboratory and instrumental investigations. In summary provided material, a comparative analysis of the clinical course of chronic bacterial prostatitis against testosterone deficiency showed more severe changes in the prostate in patients with total testosterone below 8 nmol/l.

The study involved 230 patients aged 20 to 45 years with a diagnosis of chronic bacterial prostatitis. The study found that in patients with chronic bacterial prostatitis clinical picture, in addition to pain, is a lower urinary tract symptoms, neuro-vegetative and sexual dysfunction. In patients with chronic bacterial prostatitis, recorded various sexual disorders, most of which are normalized after antibiotic therapy. Erectile dysfunction, which are recorded in patients with chronic bacterial prostatitis is psychogenic in nature dysfunction.

Influence of hypogonadism on the results of transurethral resection of the prostate (TURP) in patients with benign prostatic hyperplasia (BPH) remains unexplored. At the survey included 98 patients with benign prostatic hyperplasia who underwent TURP. Revealed that the postoperative period in patients characterized by a significant decrease in the level of performance testosteronemii in all cases, and against the background of hypogonadism accompanied by the development of more complications. Preoperative correction of hypogonadism for 2 weeks prior to surgery allows a 2-3 times lower risk of postoperative complications.

 

The results of 2500 implantations we have developed semi-rigid prostheses, made between 1981 and 2013. Demonstrated surgical technique, its high efficacy in the treatment of erectile dysfunction resistant to drug therapy, and the low rate of postoperative complications.  

We developed a questionnaire to determine the male sexuality , which is determined by sexual history retrospectively in 105 patients aged 39 to 81 years. According to the results of the survey in a group of patients with normal sexuality included 33,33%, of the men in the group with reduced sexuality 35,24%, in the group with increased sexuality – 31,43% men. It was determined that the questionnaire can effectively divide the men by their level of sexuality. A number of trusted dependency between sexuality of patients with symptomatic BPH , and the following criteria: the severity of symptoms of the lower urinary tract , the average size of the prostate gland, PSA blood, testosterone levels. Separation of patients in terms of sexuality by the author questionnaire can serve as a tool to assess the main clinical manifestations of benign prostatic hyperplasia , and also identify early signs of hypogonadism .

 

According to existing ideas erectile dysfunction is one of the symptoms of chronic pelvic pain syndrome (CPPS) associated with prostatic pathology . However, erectile dysfunction is not pathognomonic for this state. This paper presents the results of 249 patients CPPS obtained by filling out questionnaires NIH-CPSI; I-PSS; IIEF-5 . Shown separately symptomatology of inflammatory and non-inflammatory forms of CPPS . The frequency of an identified pain, symptoms of the lower urinary tract in detail the structure of erectile dysfunction and its relationship between the presence and severity of pain and urinary disorders.

 

There is presentation of paths of the pathogenesis of renal scaring from vesico-ureteral reflux at this article. Author demonstrated the role of macrophage and tissue monocyte in process of the inflammatory remodeling of interstitial renal tissue. Different cell signals affects interstitial tissue and activates fibroblast ploliferation and interstitial volume increasing. Cytokines such us monocyte chemotactic peptide-1, epidermal growth factor, macrophage colony stimulating factor, transforming growth factor-β1plays important role within process renal scaring and remodeling. Urinary tract infection causes expressed medullar renal scaring by toxins and inductive endogenic cytokines.

 

The report author shares his impressions of the Congress of the International Society of Chemotherapy infections and cancer, which took place from 5th to 8th June 2013 in Yokohama, Japan.