POWER DOPPLER IMAGING IN PATIENTS WITH SUSPECTED PROSTATE CANCER
https://doi.org/10.21886/2308-6424-2016-0-3-17-27
Abstract
Abstract. This study was aimed to evaluate the role of power Doppler imaging in diagnosis of prostate cancer and prediction of its aggressiveness. This study included 118 patients with prostate cancer suspected due to elevation of prostate specific antigen (PSA) values to > 4.0 ng/ml. All patients underwent transrectal prostate biopsy with ultrasound guidance for histological verification. Prostate was scanned in power Doppler mode and one of vascularization patterns was assigned, as described by Zhao et al. Power Doppler imaging results and biopsy results were compared. Forty eight patients had normal results of power Doppler imaging. Fifty five patients had focal enhancement of blood flow, which allowed to perform a targeted biopsy of suspected lesion. Fifteen patients had diffusely enhanced blood flow. Sensitivity of power Doppler imaging was 82.4%, specificity was 70.5%, positive and negative predictive values were 66.7% and 72.3% correspondingly. Overall accuracy for prostate cancer detection was 81.1%. Association between observed vascular patterns and Gleason score, tumor dissemination and PSA level was detected. Power Doppler imaging allows efficient detection, staging and prediction of aggressiveness of prostate cancer, when compared to standard transrectal ultrasound imaging.
About the Authors
T. V. Shatylko
Saratov State Medical University, Saratov
Russian Federation
Russian Federation
L. N. Sedova
Saratov State Medical University, Saratov
Russian Federation
Russian Federation
A. Yu. Korolev
Saratov State Medical University, Saratov
Russian Federation
Russian Federation
References
1. Jemal A. et al. Global cancer statistics // CA: A Cancer Journal For Clinicians. – 2011. – Т. 61. – №. 2. – С. 69-90.
2. Попков В. М. и др. Комбинирование трансуретральной резекции и HIFU-аблации простаты при лечении локализованного рака // Саратовский научно-медицинский журнал. – 2014. – Т. 10. – №. 3. – С. 450-455.
3. Wilson N. M. et al. Correlation of power Doppler with microvessel density in assessing prostate needle biopsy // Clinical radiology. – 2004. – Т. 59. – №. 10. – С. 946-950.
4. Шатылко Т. В., Королѐв А. Ю. Пути совершенствования ранней диагностики рака предстательной железы // Бюллетень медицинских интернет- конференций. – 2015. – Т. 5. – №. 4. – С. 264.
5. Zhao H. X., Zhu Q., Wang Z. C. Detection of prostate cancer with threedimensional transrectal ultrasound: correlation with biopsy results // The British Journal of Radiology. – 2014.
6. Коган М.И., Белоусов И.И., Болоцков А.С. Артериальный кровоток в простате при синдроме хронической тазовой боли/ хроническом простатите // Урология. – 2011. – №3. – С. 22-27.
7. Аляев Ю. Г. и др. Современные возможности эхолокациии локализованного рака предстательной железы // Врач. – 2007. – №. 10. – С. 82-84.
8. Noh T. I. et al. Are hypoechoic lesions on transrectal ultrasonography a marker for clinically significant prostate cancer? // Korean Journal of Urology. – 2013. – Т. 54. – №. 10. – С. 666-670.
9. Шатылко Т. В., Седов Д. С. Серая зона PSA: статистико-математический анализ с применением метода искусственных нейронных сетей // Бюллетень медицинских интернет-конференций. – 2014. – Т. 4. – №. 4. – С. 417.
10. Margel D. et al. Predictors of pathological progression among men with localized prostate cancer undergoing active surveillance: a sub-analysis of the REDEEM study // The Journal of Urology. – 2013. – Т. 190. – №. 6. – С. 2039-2046.
11. Попков В. М., Шатылко Т. В., Фомкин Р. Н. Прогнозирование результата патогистологического исследования простаты с помощью искусственной нейронной сети // Саратовский научно-медицинский журнал. – 2014. – Т. 10. – №. 2. – С. 328-332.
12. Briganti A. et al. Predicting the risk of bone metastasis in prostate cancer // Cancer treatment reviews. – 2014. – Т. 40. – №. 1. – С. 3-11.
13. Mohler J. L. et al. NCCN guidelines on prostate cancer // National Comprehensive Cancer Network Url: https://www.nccn.org/professionals/physician_gls/pdf/ prostate.pdf (дата обращения: 25.06.2016)
14. Motten N. et al. EAU guidelines on prostate cancer [Электронный ресурс] // European Association of Urology Url: http://uroweb.org/guideline/prostate-cancer/ (дата обращения: 25.06.2016).
Review
For citations:
Shatylko T.V., Sedova L.N., Korolev A.Yu. POWER DOPPLER IMAGING IN PATIENTS WITH SUSPECTED PROSTATE CANCER. Urology Herald. 2016;(3):17-27. (In Russ.) https://doi.org/10.21886/2308-6424-2016-0-3-17-27
Views:
1477
Email this article 
