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Recurrent course of two subtypes of retroperitoneal liposarcomas with development of end-stage hydronephrosis: a rare case report

https://doi.org/10.21886/2308-6424-2025-13-3-152-158

Abstract

Hydronephrotic transformation can result from external compression of the uretero-pelvic junction by a tumor. Without timely intervention, this may lead to irreversible loss of renal parenchyma. Retroperitoneal liposarcoma is one potential cause of such compression. This article presents a clinical case highlighting the progression of the condition and explores surgical treatment options. Special emphasis is placed on evaluating various operative approaches. Comparative analysis indicates that laparoscopic nephrectomy combined with complete resection of the liposarcoma with negative surgical margins remains the preferred strategy, as it is associated with improved patient survival outcomes.

About the Authors

A. G. Martov
Central Clinical Hospital of Civil Aviation”; Medical and Biological University of Innovation and Continuing Education — Burnazyan Federal Medical Biophysical Center of the FMBA of Russia; Medical Scientific and Educational Center — Lomonosov Moscow State University (Lomonosov University)
Russian Federation

Alexey G. Martov — Dr.Sc.(Med), Full Prof., Corr. Member of the RAS.

Moscow


Competing Interests:

The authors declare no conflicts of interest



A. M. Pshikhachev
Central Clinical Hospital of Civil Aviation”; Medical Scientific and Educational Center — Lomonosov Moscow State University (Lomonosov University)
Russian Federation

Akhmed M. Pshikhachev — Dr.Sc.(Med).

Moscow


Competing Interests:

The authors declare no conflicts of interest



D. Yu. Zavarzin
Medical and Biological University of Innovation and Continuing Education — Burnazyan Federal Medical Biophysical Center of the FMBA of Russia
Russian Federation

Competing Interests:

The authors declare no conflicts of interest



S. V. Dutov
Central Clinical Hospital of Civil Aviation”; Medical and Biological University of Innovation and Continuing Education — Burnazyan Federal Medical Biophysical Center of the FMBA of Russia
Russian Federation

Сергей Валерьевич Дутов — канд. мед. наук.

Москва


Competing Interests:

The authors declare no conflicts of interest



D. A. Abdullaev
Central Clinical Hospital of Civil Aviation”
Russian Federation

David A. Abdullaev — Сand.Sc.(Med).

Moscow


Competing Interests:

The authors declare no conflicts of interest



A. S. Andronov
Central Clinical Hospital of Civil Aviation”; Medical and Biological University of Innovation and Continuing Education — Burnazyan Federal Medical Biophysical Center of the FMBA of Russia
Russian Federation

Andrey S. Andronov — Сand.Sc.(Med).

Moscow


Competing Interests:

The authors declare no conflicts of interest



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Review

For citations:


Martov A.G., Pshikhachev A.M., Zavarzin D.Yu., Dutov S.V., Abdullaev D.A., Andronov A.S. Recurrent course of two subtypes of retroperitoneal liposarcomas with development of end-stage hydronephrosis: a rare case report. Urology Herald. 2025;13(3):152-158. (In Russ.) https://doi.org/10.21886/2308-6424-2025-13-3-152-158

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ISSN 2308-6424 (Online)