The aim of this study was to evaluate changes in tubulointerstitial renal parenchyma in patients with nephrolithiasis at various stages of surgical treatment using mediators nephrofibrosis and angiogenesis and the results of intraoperative biopsy of kidney. Results of surgical treatment of 65 patients with nephrolithiasis were studied. In serum and urine of patients content determined molecular mediators that characterize nephrosclerosis. It is shown that the most informative markers of tubulointerstitial fibrosis are IL12, VEGF in serum and excreted in the urine β2 MG, MCP 1 and NO. High level markers nephrosclerosis, conserved in the postoperative period in patients with bilateral nephrolithiasison the background existing tubulointerstitial damage indicates irreversibility nephrosclerosis and further progression of chronic kidney disease.

Based on a investigation 92 children aged 6 to 15 years with enuresis shown to be effective use of physiotherapy in combination with a minimum dose of oxybutynin (2.5 mg at night). Physiotherapy is a combination of two types of magnetic therapy – transcranial method for bitemporal and cervical sympathetic ganglia on the neck-collar method. Therapeutic effect as reliever enuresis achieved in 76.6% of children. Positive dynamics of enuresis associated with the correction and improvement of adaptation hypersympathicotonia and autonomic nervous system.

The results of a prospective study of 32 boys 11-15 years, underwent orchiopexy about unilateral cryptorchidism are presented in article. The evaluation of pubertal development, testicular ultrasound and doppler, prostate investigation and the tests of serum reproductive hormones were performed. The examination were found the reduced gonads volume side orhiopexy determined at the initiation of puberty and expanded as it progresses, degenerative changes of the prostate gland . There were not significant changes in serum gonadotropins and testosterone.

 

The article contains a literature review is devoted to the problem of varicocele, tactics of patients with this pathology and the determination of indications for surgical treatment.

 

During the last century various loop operations are used in the treatment of stress urinary incontinence. Methods for treating urinary incontinence are inextricably linked with the development of urology as a science. Dominance concept of sphincter deficiency as the main cause of urinary incontinence led to the use of various muscle loops, which was considered by many authors, could carry the functional load. The last decade was marked by significant developments and achievements in the treatment of urinary incontinence in women. Data received today entitle say that, in general, the use of synthetic loops installed without tension in the middle of the urethra, to get rid of urinary incontinence significant number of patients with this medical and social problem worldwide. We can say that with the advent of SIMS and their use in the treatment of urinary incontinence, a new stage. The concept of using SIMS for implantation which the surgeon requires one incision under the middle third of the urethra, is not innovative. So Smith presented his minisling made of pig skin in 1987. First available for use SIMS became minisling TVT Secur company Gynaecare (Ethicon) in 2005. To date, there are many SIMS: TVT Secur®, MiniArc®, Ophira®, Adjust®, Solyx®, Zipper Sling®, Prosurg®, Tissue Fixation System®, Needleless®, Altis®, Just-swing®, Desara®. Many manufacturers do not stop and continue to develop new minislingi with new locking mechanisms.

The lecture presents a modern view of the anatomical and functional properties of the bladder on the mechanisms leading to its dysfunction. The study is based on an analysis of the national literature of recent decades. 

The article presents a report on section oncological urology 11th Congress of the European Association of Urology, held in Prague from 17 to 19 January 2014. Key words: 11th Congress, European Association of Urology, Prague