The article represents the study of survival rate (common, oncology-specific, disease-free) and frequency and nature of the recurrence after organ-saving surgery of patients with muscleinvasive bladder cancer stages T2b and T3aN0M0G1-G3 with full diagnosis of bladder mucosa, the adjuvant intravesical chemotherapy on pre-operative stage. Oncology-speсific and diseasefree survival 5-year rates with full diagnosis of bladder mucosa, the adjuvant intravesical chemotherapy on pre-operative stage were higher. Recurrence of bladder cancer were on the fields, other than the zones of operations, the stages of disease were lower than that of the original tumor. These factors indicated the presence of an unrecognized cancer in situ on the walls of the urine bladder.

Studied involvement of nonclostridial anaerobic bacteria in the etiology of acute obstructive pyelonephritis using the example of the pathology in animals. In experiment animals (rabbits) were divided into 4 groups and infected common pathogen (E.coli), and 3 types of anaerobic bacteria (Peptococcus niger, Eubacterium saburreum, Propionibacterium acnes). Results of research suggest that nonclostridial anaerobic organisms cause identical morphological changes in the kidney parenchyma, as the all-proved pathogen, however the severity of clinical symptoms, the severity of the toxic syndrome depend on the type of nonclostridial anaerobic bacteria.

A study of staghorn nephrolithiasis pathogenesis with aim of stone prevention has particular importance. Knowledge of urine stones’ chemical structure is a basic in individual metaphylaxis. A complex biochemical analysis of blood and 24-hours urine for mineral disturbances detection in 136 patients with staghorn stones was performed. An x-ray analysis for detection a mineral structure of 130 stones was done. An analysis of chemical structure of stones and blood biochemical disturbances showed the typical changes of metabolism in specific stones only in 56,9% cases, which make an understanding of processes underlying stone formation more complicated.

Bacteriological results of prostatic tissue in benign prostatic hyperplasia and prostate cancer are shown in this article. A use of extended amount of media for bacterial isolation allows a wide spectrum of nonclostridial anaerobic (Bacteroides sp., Bifidobacterium sp., Eubacterium sp., Propionibacterium sp., Рeptococcus sp., Peptostreptococcus sp., Prevotella sp., Veilonella sp., Fusobacterium sp., Streptococcus sp., Capnocytophaga ochracea) and aerobic bacteria (Corynebacterium sp., Enterococcus sp., E. coli, S. haemolyticus, S. hominis). It is revealed that nonclostridial anaerobes are predominant flora in qualitative and quantitative terms in prostate cancer as well as benign prostatic hyperplasia. Both a mean level of bacterial contamination of prostate bioptates and incidence rate of most bacteria was higher in patients with benign prostatic hyperplasia.

The study involved 124 patients aged 20-45 years with a diagnosis of chronic bacterial prostatitis. In 37% of patients with chronic bacterial prostatitis testosterone was below the standard indicators. The study revealed that the majority of patients with chronic bacterial prostatitis, with a deficit of general clinical picture of Tc addition to pain presented various forms of sexual dysfunction, as well as lower urinary tract symptoms. In assessing the clinical performance more pronounced changes were observed in patients with decreased testosterone levels in comparison with patients with normal testosterone levels.

The article presents the clinical and statistical analysis of the causes, options for localization zones and the length of the urethra with multifocal lesions and extended SU 106 patients. It is these parameters are decisive for the choice of surgical options for this disease, which is only half of the cases can be cured by a momentary interference. Other patients usually require a multi-stage surgery.

This article presents the results of treatment of patients with ureterolithiasis, who had the transurethral ureterolithotripsy. The article demonstrated the advantages and disadvantages of various kinds of energy at endoscopic treatment of ureterolithiasis.

This article contains literary review of world scientific papers of over the last 30 years dedicated to the use of different types of augmenting substances in treatment vesicoureteral reflux, formulated the main requirements to their specifications.