CLINICAL CASE OF NEPHROPATHY CAUSED BY THE RECEPTION OF THE AGRIMONIA EUPATORIA
https://doi.org/10.21886/2308-6424-2013-0-3-30-38
Abstract
The article describes the clinical observation of toxic chronic tubulointerstitial nephritis due to prolonged use of herbal drug Agrimonia Eupatoria. The toxic effects of A.Eupatoria more associated not with specific toxicants, and the presence of a large number of coumarin glycosides and its metabolites. Earlier in the literature descriptions of nephrotoxicity A.Eupatoria ordinary does not. In conducting the study of the morphological characteristics were described tubulopathy, characterized by a pronounced hydropic dystrophy tubular epithelium up to vacuolization, weak and small focal diffuse interstitial fibrosis. Special attention in the clinical picture itself drawn the progressive increase in proteinuria, hypertension due to lower filtration function of the kidney and renal tubular dysfunction. Key words: toxic nephropathy, Agrimony ordinary, Agrimonia Eupatoria, coumarin, phytotoxins
About the Authors
M. M. Batyushin
Department of Internal Disease with Physiotherapy №2, Department of Nephrology Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
N. A. Sadovnichaya
Department of Internal Disease with Physiotherapy №2, Department of Nephrology Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
L. I. Rudenko
Department of Internal Disease with Physiotherapy №2, Department of Nephrology Rostov State Medical University, Rostov-on-Don
Russian Federation
Russian Federation
P. E. Povilaitite
Rostov Regional Office for autopsy, Rostov-on-Don
Russian Federation
Russian Federation
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Review
For citations:
Batyushin M.M., Sadovnichaya N.A., Rudenko L.I., Povilaitite P.E. CLINICAL CASE OF NEPHROPATHY CAUSED BY THE RECEPTION OF THE AGRIMONIA EUPATORIA. Urology Herald. 2013;(3):30-38. (In Russ.) https://doi.org/10.21886/2308-6424-2013-0-3-30-38
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