Preview

Urology Herald

Advanced search

Combination of CAKUT-syndrome and axial skeletal abnormalities

https://doi.org/10.21886/2308-6424-2022-10-2-124-130

Abstract

Combined anomalies of the urinary system and axial skeleton, including an L-shaped kidney, obstruction of the ureteropelvic junction (CAKUT syndrome, congenital anomalies of the kidney and urinary tract syndrome) and spinal anomalies, are extremely rare. The clinical case gives a description of a similar combined developmental anomaly.

About the Authors

O. A. Kaplunova
Rostov State Medical University
Russian Federation

Olga A. Kaplunova – M.D., Dr.Sc.(Med), Full Prof.; Prof., Dept. of Anatomy 

29 Nakhichevanskiy Ln., Rostov-on-Don, 344022



E. V. Chaplygina
Rostov State Medical University
Russian Federation

Elena V. Chaplygina – M.D., Dr.Sc.(Med), Full Prof.; Head, Dept. of Anatomy 

29 Nakhichevanskiy Ln., Rostov-on-Don, 344022



M. M. Batiushin
Rostov State Medical University
Russian Federation

Mikhail M. Batiushin – M.D., Dr.Sc.(Med), Full Prof.; Prof., Dept. of Internal Medicine No.2 

29 Nakhichevanskiy Ln., Rostov-on-Don, 344022



O. P. Sukhanova
Rostov State Medical University
Russian Federation

Olga P. Sukhanova – M.D.; Assist.Prof., Dept. of Radiation Diagnostics 

29 Nakhichevanskiy Ln., Rostov-on-Don, 344022



I. M. Blinov
Rostov State Medical University
Russian Federation

Igor M. Blinov – M.D.; Division of Magnetic Resonance Imaging and Computed Tomography 

29 Nakhichevanskiy Ln., Rostov-on-Don, 344022



E. D. Stefanova
Rostov State Medical University
Russian Federation

Elizaveta D. Stefanova – Student, Pediatric Faculty 

29 Nakhichevanskiy Ln., Rostov-on-Don, 344022



A. M. Batiushina
Rostov State Medical University
Russian Federation

Alla M. Batiushina – Student, Pediatric Faculty 

29 Nakhichevanskiy Ln., Rostov-on-Don, 344022



References

1. Vior M.P., Santos F. Normal and pathological development of the kidneys. In: Leumanna E., Tsygin A.N., Sarkisyan A.A., eds. Pediatric Nephrology. Moscow: Litera. 2010; 23-27. (In Russ.).

2. Kutyrlo IE, Savenkova ND. Cakut–syndrome in children. Nephrology (Saint-Petersburg). 2017;21(3):18-24. (In Russ.). DOI: 10.24884/1561-6274-2017-3-18-24.

3. Ingelfinger J.R., Kalantar-Zadeh K., Schaefer F. Averting the legacy of kidney disease-focus on childhood. Nephrology (Saint-Petersburg). 2016;20(2):10-17. (In Russ.). eLIBRARy ID: 25673179.

4. Renkema Ky, Winyard PJ, Skovorodkin IN, Levtchenko E, Hindryckx A, Jeanpierre C, Weber S, Salomon R, Antignac C, Vainio S, Schedl A, Schaefer F, Knoers NV, Bongers EM; EUCAKUT consortium. Novel perspectives for investigating congenital anomalies of the kidney and urinary tract (CAKUT). Nephrol Dial Transplant. 2011;26(12):3843-51. DOI: 10.1093/ndt/gfr655.

5. Talati AN, Webster CM, Vora NL. Prenatal genetic considerations of congenital anomalies of the kidney and urinary tract (CAKUT). Prenat Diagn. 2019;39(9):679-92. DOI: 10.1002/pd.5536.

6. Avanoglu A, Tiryaki S. Embryology and Morphological (Mal)Development of UPJ. Front Pediatr. 2020;8:137. DOI: 10.3389/fped.2020.00137.

7. Al Aaraj MS, Badreldin AM. Ureteropelvic Junction Obstruction. [Updated 2022 Apr 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560740/ Accessed May 26, 2022.

8. Pupca G, Miclăuş GD, Bucuraş V, Iacob N, Sas I, Matusz P, Tubbs RS, Loukas M. Left crossed fused renal ectopia L-shaped kidney type, with double nutcracker syndrome (anterior and posterior). Rom J Morphol Embryol. 2014;55(3 Suppl):1237-41. PMID: 25607413.

9. Mudoni A, Caccetta F, Caroppo M, Musio F, Accogli A, Zacheo MD, Burzo MD, Nuzzo V. Crossed fused renal ectopia: case report and review of the literature. J Ultrasound. 2017;20(4):333-37. DOI: 10.1007/s40477-017-0245-6.

10. Vivante A, Kohl S, Hwang Dy, Dworschak GC, Hildebrandt F. Single-gene causes of congenital anomalies of the kidney and urinary tract (CAKUT) in humans. Pediatr Nephrol. 2014;29(4):695-704. DOI: 10.1007/s00467-013-2684-4.

11. Capone VP, Morello W, Taroni F, Montini G. Genetics of Congenital Anomalies of the Kidney and Urinary Tract: The Current State of Play. Int J Mol Sci. 2017;18(4):796. DOI: 10.3390/ijms18040796.

12. Pope JC 4th, Brock JW 3rd, Adams MC, Stephens FD, Ichikawa I. How they begin and how they end: classic and new theories for the development and deterioration of congenital anomalies of the kidney and urinary tract, CAKUT. J Am Soc Nephrol. 1999;10(9):2018-28. DOI: 10.1681/ASN.V1092018.

13. Murugapoopathy V, Gupta IR. A Primer on Congenital Anomalies of the Kidneys and Urinary Tracts (CAKUT). Clin J Am Soc Nephrol. 2020;15(5):723-31. DOI: 10.2215/CJN.12581019.


Review

For citations:


Kaplunova O.A., Chaplygina E.V., Batiushin M.M., Sukhanova O.P., Blinov I.M., Stefanova E.D., Batiushina A.M. Combination of CAKUT-syndrome and axial skeletal abnormalities. Urology Herald. 2022;10(2):124-130. (In Russ.) https://doi.org/10.21886/2308-6424-2022-10-2-124-130

Views: 1325


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2308-6424 (Online)