Xanthogranulomatous pyelonephritis in a 7-year-old girl
https://doi.org/10.21886/2308-6424-2020-8-1-99-109
Abstract
The paper presents a case history of xanthogranulomatous pyelonephritis that developed in a 7-year-old girl in combination with urolithiasis background. Our available sources for the last 50 years contain only 283 descriptions of pediatric xanthogranulomatous pyelonephritis (XGP) cases. We were able to find in domestic publications descriptions of two clinical observations of histologically proven XGP in children of 15 and 17 years. Clinical manifestations of the disease, radiological imaging data, and laboratory findings during the initial three months of the condition fit the disease pattern of a diffuse acute pyelonephritis. A remarkable peculiarity of the presented case was in the two-month interval during which the girl with a severe destructive renal process remained under medical supervision as an outpatient, suffered no pain, and had normal urinalysis results. Nephrectomy was performed from lumbotomy access considering clinical manifestations, data from laboratory and radiological isotope studies. The postoperative period was complicated by the development on the 2nd day of acute perforation of a duodenal ulcer. The intensity of perinephric process was unique and never encountered in our earlier practice. The described changes made kidney exposure extremely difficult. Therefore, nephrectomy should be carried out exclusively in the national highly specialized pediatric urological centers.
About the Authors
V. V. SizonovRussian Federation
Vladimir V. Sizonov – M.D., Dr. Sc. (M).; Assoc. Prof. (Docent);Prof., Department of Urology and Human Reproductive Health (with the Pediatric Urology and Andrology Course); Head, Pediatric Urology and Andrology Division
M. I. Kogan
Russian Federation
Mikhail I. Kogan – Honored Scientist of Russian Federation, M.D., Dr. Sc. (M), Full Prof.; Head, Dept. of Urology and Human Reproductive Health (with the Pediatric Urology and Andrology course)
I. I. Babich
Russian Federation
Igor I. Babich – M.D., Dr. Sc. (M), Full Prof.; Prof., Dept. of Surgery No. 4; Pediatric Surgeon, Pediatric Surgery Division
A. KH-A. Shidaev
Russian Federation
Askhab Kh-A. Shidaev – Resident, Dept. of Pediatric Surgery and Orthopedics
O. A. Shaldenko
Russian Federation
Olesya A. Shaldenko – M.D.; Pediatric Urologist and Andrologist, Pediatric Urology and Andrology Division
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Review
For citations:
Sizonov V.V., Kogan M.I., Babich I.I., Shidaev A.Kh., Shaldenko O.A. Xanthogranulomatous pyelonephritis in a 7-year-old girl. Urology Herald. 2020;8(1):99-109. (In Russ.) https://doi.org/10.21886/2308-6424-2020-8-1-99-109