Prostate pathological evaluation after radical prostatectomy
https://doi.org/10.21886/2308-6424-2019-7-1-74-83
Abstract
The article presents information about the prostate's zonal structure, prostate preparation after radical prostatectomy, cancer incidence in different prostate areas. This provides an overview of the WHO classification (2016) of prostate tumors, the changes are noted, approaches to the diagnosis of cancer variants, Gleason score assessment, gradation determination, clinical prognostic risk groups for prostate cancer, primary tumor assessment according to the international classification of prostate cancer according to the TNM system (AjCC 8th ed.), which was supplemented and revised in 2017. Prognostic factors for acinar carcinoma and the role of immunohistochemical diagnosis in the morphological material were determined. In conclusion, the main significant parameters are indicated, which should be reflected in the Protocol of in vivo pathoanatomical study of the prostate samples after radical prostatectomy.
About the Author
T. O. Lapteva
Rostov Research Institute of Oncology
Russian Federation
Russian Federation
Tatyana O. Lapteva - M.D., Pathologist, Pathology Division.
Rostov-on-Don, tel.: +7 (988) 533-46-45
References
1. Stamey TA, Yemoto CM, McNeal JE, Sigal BM, Johnstone IM. Prostate cancer is highly predictable: a prognostic equation based on all morphological variables in radical prostatectomy specimens. J Urol. 2000;163(4):1155-1160. PMID: 10737486
2. Pushkar' DYu, Govorov AV, Sidorenkov AV, Prilepskaya EA, Kovylina MV. Rannyaya diagnostika raka predstatel'noy zhelezy. Metodicheskie rekomendatsii №19. M.: ID «ABV-press»; 2015:8-9. (In Russ.)
3. Berney DM, Beltran L, Fisher G, North BV, Greenberg D, M0ller H, Soosay G, Scardino P, Cuzick J. Validation of a contemporary prostate cancer grading system using prostate cancer death as outcome. Br J Cancer. 2016;114(10):1078-1083. DOI: 10.1038/bjc.2016.86
4. Moch H, Humphrey PA, Ulbright TM, Reuter VE, eds. WHO Classification of Tumours of the Urinary System and Male Genital Organs. vol. 8. 4th ed. WHO Press; 2016. ISBN-13 (Print Book) 978-92-832-2437-2.
5. Frank GA, Andreeva YuYu, Moskvina LV, Efremov GD, Samoilova SI. A new WHO classification of prostate tumors. Arkhivpatologii. 2016;78(4):32-42. DOI: 10.17116/patol201678432-42 (In Russ.)
6. Gorban' NA, Kudaybergenova AG. Trepanobiopsiya predstatel'noy zhelezy: vzglyad morfologa. M.: ID «ABV-press»; 2017:101-117. (In Russ.)
7. Adam M, Hannah A, Budaus L, Steuber T, Salomon G, Michl U, Haese A, Fisch M, Wittmer C, Steurer S, Minner S, Heinzer H, Huland H, Graefen M, Sauter G, Schlomm T, Isbarn H. A tertiary Gleason pattern in the prostatectomy specimen and its association with adverse outcome after radical prostatectomy. J Urol. 2014;192(1):97-101. DOI: 10.1016/j.juro.2014.01.029
8. Andreevoy YuYu, Franka GA eds. Opukholimochevydelitel'noy sistemy i muzhskikh polovykh organov. Morfologicheskaya diagnostika i genetika: Rukovodstvo dlya vrachey. M.: Prakticheskaya Meditsina; 2012:110-167. (In Russ.)
Review
For citations:
Lapteva T.O. Prostate pathological evaluation after radical prostatectomy. Urology Herald. 2019;7(1):74-83. (In Russ.) https://doi.org/10.21886/2308-6424-2019-7-1-74-83
Views:
23114
Email this article 
