ONCOLOGICAL RESULTS OF PRIMARY, SALVAGE AND PALLIATIVE CISTECTOMY OF BLADDER CANCER
https://doi.org/10.21886/2308-6424-2017-5-1-12-19
Abstract
Introduction. Modern studies show an impressive 5-year absence of pelvic recurrence in 80% to 90% of cases and a 5-year overall and cancer-specific survival of 59% to 60% and 55% to 65% for radical cystectomy (RCE), respectively.
Objective. Analysis of the results of radical and palliative treatment in patients with bladder cancer.
Materials and methods. The study included 349 patients exposed to RCE, of which three groups were identified: RCE primary (n = 206), salvage RCE (n = 119) and CE palliative (n = 24). Calculation of survival rates for the years of follow-up was performed according to the Kaplan-Meier method, taking into account consecutive elimination from the analysis of patients.
Results. Based on the results of the performed analysis, it was established that significantly worse indices for all types of survival were revealed in palliative CE. Comparing the oncological effectiveness of primary and salvage RCE, there is no statistically significant difference in survival rates in the compared groups.
Conclusions. RCE should not be considered as second-line therapy, but in the presence of indications as a primary medical approach. The performance of early salvage RCE with progression of bladder cancer against the background of organ-preserving treatment provides oncological results similar to those in primary RCE.
About the Authors
O. N. Vasil’ev
Rostov State Medical University
Russian Federation
Russian Federation
M. I. Kogan
Rostov State Medical University
Russian Federation
Russian Federation
V. A. Perepechay
Rostov Clinical Hospital of the Southern Federal District Medical Center
Russian Federation
Russian Federation
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Review
For citations:
Vasil’ev O.N., Kogan M.I., Perepechay V.A. ONCOLOGICAL RESULTS OF PRIMARY, SALVAGE AND PALLIATIVE CISTECTOMY OF BLADDER CANCER. Urology Herald. 2017;5(1):12-19. (In Russ.) https://doi.org/10.21886/2308-6424-2017-5-1-12-19
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