Atypical manifestation of embryonal testicular cancer as a cystic structure: a case report
https://doi.org/10.21886/2308-6424-2025-13-6-148-154
Abstract
Intratesticular cysts have recently become a common finding in clinical practice. According to research data, such formations are detected in 8.0 – 9.8% of men. Simple intratesticular cysts do not have malignant potential and do not require monitoring or treatment. However, it is crucial to differentiate them from cystic neoplasms, which may conceal malignant processes. This article presents a clinical case of a 30-year-old patient in whom ultrasonography revealed a cystic formation in the right testis with a minimal solid component measuring 7.1 × 6.9 × 8.5 mm. Initially, active surveillance with regular ultrasound monitoring was chosen. However, progressive enlargement of the lesion required surgical intervention. Given the small size of the tumor, an attempt was made at testis-sparing surgery. However, intraoperative morphological examination using frozen sections revealed the malignant nature of the lesion, leading to the performance of a radical inguinal orchiectomy. The final histological examination confirmed the diagnosis of embryonal carcinoma. This clinical case demonstrates an atypical manifestation of embryonal testicular carcinoma in the form of a predominantly cystic lesion with a minimal solid component. The presented case complements existing data on the ultrasound characteristics of embryonal carcinoma and highlights the importance of careful active surveillance even for small cystic formations in testis.
About the Authors
A. I. RyzhkovРоссия
Aleksei I. Ryzhkov – Cand.Sc.(Med)
Yaroslavl
S. Y. Sokolova
Россия
Svetlana Yu. Sokolova
Yaroslavl
A. E. Vasileva
Россия
Alexandra E. Vasileva
Yaroslavl
E. V. Gurin
Россия
Eduard V. Gurin
Yaroslavl
A. V. Borisov
Россия
Alexey V. Borisov
Yaroslavl
M. M. Vorchalov
Россия
Mikhail M. Vorchalov – Cand. Sc.(Med)
Yaroslavl
I. S. Shormanov
Россия
Igor S. Shormanov – Dr. Sc.(Med), Full Prof.
Yaroslavl
References
1. Gooding GA, Leonhardt W, Stein R. Testicular cysts: US findings. Radiology. 1987;163(2):537-538. DOI: 10.1148/radiology.163.2.3550884
2. Leung ML, Gooding GA, Williams RD. High-resolution sonography of scrotal contents in asymptomatic subjects. AJR Am J Roentgenol. 1984;143(1):161-164. DOI: 10.2214/ajr.143.1.161
3. Isidori AM, Lenzi A. Ultrasound of the Testis for the Andrologist: Morphological and Functional Atlas. Springer, 2018. DOI: 10.1007/978-3-319-51826-8
4. Höbarth K, Kratzik C. High resolution ultrasonography in the diagnosis of simple intratesticular cysts. Br J Urol. 1992;70(5):546-549. PMID: 1467863
5. Rifkin MD, Jacobs JA. Simple testicular cyst diagnosed preoperatively by ultrasound. J Urol. 1983;129(5):982-983. DOI: 10.1016/s0022-5347(17)52498-2
6. Kao CS, Ulbright TM, Young RH, Idrees MT. Testicular embryonal carcinoma: a morphologic study of 180 cases highlighting unusual and unemphasized aspects. Am J Surg Pathol. 2014;38(5):689-697. DOI: 10.1097/PAS.0000000000000171
7. Kucuk S, Kucuk IG, Mizrak B, Öngel K. Pure embryonal carcinoma of the testis in an adult male patient: case report. Sănătate Publică, Economie și Management în Medicină. 2021;(1):26-30.
8. Khan L, Verma S, Singh P, Agarwal A. Testicular embryonal carcinoma presenting as chest wall subcutaneous mass. J Cytol. 2009;26(1):39-40. DOI: 10.4103/0970-9371.54868
9. Oyen RH. Scrotal ultrasound. Eur Radiol. 2002;12(1):19-34. DOI: 10.1007/s00330-001-1224-y
10. Gerber D, Wright HC, Sussman RD, Stamatakis L. Embryonal carcinoma presenting as a calcified solitary testicular mass on ultrasound. BMJ Case Rep. 2017;2017:bcr2017220081. DOI: 10.1136/bcr-2017-220081
11. Chowdhury W, Lodhi MU, Syed IA, Rahim U, Rahim M. Mature Testicular Teratoma with a Focus of Embryonal Carcinoma: A Case Report and Review of Literature. Cureus. 2018;10(3):e2329. DOI: 10.7759/cureus.2329
12. Gentile G, Brunocilla E, Franceschelli A, Schiavina R, Pultrone C, Borghesi M, Romagnoli D, Cevenini M, Dababneh H, Corcioni B, Gaudiano C, Gacci M, Golfieri R, Martorana G, Colombo F. Can testis-sparing surgery for small testicular masses be considered a valid alternative to radical orchiectomy? A prospective single-center study. Clin Genitourin Cancer. 2013;11(4):522-526. DOI: 10.1016/j.clgc.2013.04.033
13. Niemczyk G, Zapała Ł, Borkowski T, Szabłoński W, Radziszewski P, Cudnoch-Jędrzejewska A. Feasibility of active surveillance in small testicular mass: a mini review. Cent European J Urol. 2021;74(1):10-13. DOI: 10.5173/ceju.2021.0268
14. Nason GJ, Aditya I, Leao R, Anson-Cartwright L, Jewett MAS, O’Malley M, Sweet J, Hamilton RJ. Partial orchiectomy: The Princess Margaret cancer centre experience. Urol Oncol. 2020;38(6):605.e19-605.e24. DOI: 10.1016/j.urolonc.2020.03.012
15. Fankhauser CD, Roth L, Kranzbühler B, Eberli D, Bode P, Moch H, Oliveira P, Ramani V, Beyer J, Hermanns T. The Role of Frozen Section Examination During Inguinal Exploration in Men with Inconclusive Testicular Tumors: A Systematic Review and Meta-analysis. Eur Urol Focus. 2021;7(6):1400-1402. DOI: 10.1016/j.euf.2020.06.019
Review
For citations:
Ryzhkov A.I., Sokolova S.Y., Vasileva A.E., Gurin E.V., Borisov A.V., Vorchalov M.M., Shormanov I.S. Atypical manifestation of embryonal testicular cancer as a cystic structure: a case report. Urology Herald. 2025;13(6):148-154. (In Russ.) https://doi.org/10.21886/2308-6424-2025-13-6-148-154
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