Palliative Radiation Therapy in patients with Oncology urological diseases: a component of complex treatment of Metastatic Bone Lesions
https://doi.org/10.21886/2308-6424-2019-7-3-23-28
Abstract
Background. Patients with first diagnosed prostate cancer, kidney cancer and bladder cancer, more than 25% of cases are diagnosed at stage IV disease at the primary visit in clinics. A characteristic feature of these types of tumors is a predisposition to bone metastasis. Bones failure at the treatment stages is diagnosed in 80% of patients already.
Objectives. Determine the most effective palliative analgesic radiotherapy regimens.
Materials and methods. Case histories of 41 patients with a diagnosis of osteolytic bone lesion were analyzed. The male / female ratio is 32/9. All patients underwent radiotherapy in the Radiological Division of the Rostov District Oncological Dispensary for the period from 2015 to 2018
Results. The direct effectiveness of the analgesic effect of large-fraction radiotherapy is slightly higher than that of single-fraction radiotherapy. However, the opposite trend was observed a month after the R-therapy end. It was determined that higher analgesic effect corresponds to higher values of a single focal dose (SFD).
Conclusion. This method deserves closer attention despite the low direct efficiency of single-fraction radiation. This is due to the high and persistent analgesic activity and the short duration of the course
About the Authors
F. R. Dzhabarov
Rostov State Medical University
Russian Federation
Russian Federation
Farhad R. Dzhabarov ‒ M.D., Ph.D. (M), D.M.S.; Associate Professor, Dept. of Radiation Diagnostics
Rostov-on-Don
A. B. Alnikin
Rostov State Medical University
Russian Federation
Russian Federation
Alexander B. Alnikin ‒ M.D., Ph.D. doct. cand. (M); Assistant, Dept. of Surgiacal Diseases No.2; Deputy Director for Clinical Service
Rostov-on-Don
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Review
For citations:
Dzhabarov F.R., Alnikin A.B. Palliative Radiation Therapy in patients with Oncology urological diseases: a component of complex treatment of Metastatic Bone Lesions. Urology Herald. 2019;7(3):23-28. (In Russ.) https://doi.org/10.21886/2308-6424-2019-7-3-23-28
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