Encrusting cystitis caused by Corynebacterium urealyticum
O. Yu. Nesterova,
V. K. Dzitiev,
N. I. Sorokin,
A. A. Strigunov,
I. A. Zhestkov,
A. G. Korobova,
A. V. Kadrev,
R. M. Gorbunov,
D. A. Filatova,
A. A. Kamalov https://doi.org/10.21886/2308-6424-2025-13-1-88-98
Abstract
Incrusting cystitis is an extremely uncommon form of chronic bladder inflammation. It is characterised by wall calcification and associated with urease-producing microorganisms, most commonly Corynebacterium urealyticum. The enzyme urease triggers a cascade of urea cleavage into carbon dioxide and ammonia, thereby leading to hyperammoniuria and urine alkalisation within the first 24 hours. These conditions result in hypersaturation favourable for the formation of struvite and apatite crystals encrusting the bladder wall. The most significant predisposing conditions and risk factors for the development of encrusting cystitis are foreign bodies in the urinary system, such as urethral catheter, nephrostomy tube, internal ureteral stents. Additionally, a history of endoscopic surgery on the urinary tract is of special importance. This article presents a clinical case of successful treatment of encrusting cystitis in a man after transurethral resection of the prostate.
About the Authors
O. Yu. Nesterova
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Olga Yu. Nesterova — Cand.Sc.(Med)
Moscow
V. K. Dzitiev
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Vitaly K. Dzitiev — Cand.Sc.(Med)
Moscow
N. I. Sorokin
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Nikolay I. Sorokin — Dr.Sc.(Med)
Moscow
A. A. Strigunov
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Andrey A. Strigunov — Cand.Sc.(Med)
Moscow
I. A. Zhestkov
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Ivan A. Zhestkov
Moscow
A. G. Korobova
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Anna G. Korobova — Cand.Sc.(Med)
Moscow
A. V. Kadrev
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Alexey V. Kadrev — Cand. Sc. (Med)
Moscow
R. M. Gorbunov
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Roman M. Gorbunov
Moscow
D. A. Filatova
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Daria A. Filatova
Moscow
A. A. Kamalov
Lomonosov Moscow State University (Lomonosov University)
Russian Federation
Russian Federation
Armais A. Kamalov — Dr.Sc.(Med), Full Prof., Acad. of the RAS
Moscow
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For citations:
Nesterova O.Yu., Dzitiev V.K., Sorokin N.I., Strigunov A.A., Zhestkov I.A., Korobova A.G., Kadrev A.V., Gorbunov R.M., Filatova D.A., Kamalov A.A. Encrusting cystitis caused by Corynebacterium urealyticum. Urology Herald. 2025;13(1):88-98. (In Russ.) https://doi.org/10.21886/2308-6424-2025-13-1-88-98
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