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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2024-12-4-43-49</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-919</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Оценка донорского участка ротовой полости в раннем и позднем послеоперационном периоде при аугментационной и заместительной уретропластике</article-title><trans-title-group xml:lang="en"><trans-title>Oral donor site evaluation in the early and late postoperative periods for augmentation and replacement urethroplasty</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6271-0556</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ирицян</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Iritsyan</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирицян Михаил Матевосович — канд. мед. наук.</p><p>Москва</p></bio><bio xml:lang="en"><p>Mikhail M. Iritsyan — Cand.Sc.(Med).</p><p>Moscow</p></bio><email xlink:type="simple">misha-res@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1643-0836</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клименко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimenko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клименко Алексей Алексеевич.</p><p>Москва</p></bio><bio xml:lang="en"><p>Aleksey A. Klimenko.</p><p>Moscow</p></bio><email xlink:type="simple">Dr.KlimenkoAA@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1472-3843</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Манцов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mantsov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Манцов Артём Андреевич.</p><p>Москва</p></bio><bio xml:lang="en"><p>Artyom A. Mantsov.</p><p>Moscow</p></bio><email xlink:type="simple">mantsow2016@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-8639-0384</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суюндиков</surname><given-names>И.-Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Suyundikov</surname><given-names>I.-N. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Суюндиков Ислам-Нури Кельдимуратович.</p><p>Москва</p></bio><bio xml:lang="en"><p>Islam-Nuri K. Suyundikov.</p><p>Moscow</p></bio><email xlink:type="simple">slamnuri@icloud.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-5108-8034</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бут</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>But</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бут Алексей Петрович.</p><p>Москва</p></bio><bio xml:lang="en"><p>Aleksey P. But.</p><p>Moscow</p></bio><email xlink:type="simple">alekseybooth@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-6434-9374</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рахматов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakhmatov</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рахматов Рустамджон Амирджонович.</p><p>Москва</p></bio><bio xml:lang="en"><p>Rustamdzhon A. Rakhmatov.</p><p>Moscow</p></bio><email xlink:type="simple">rahmatov7777@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-8480-2255</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Присмакова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prismakova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Присмакова Мария Вячеславовна.</p><p>Москва</p></bio><bio xml:lang="en"><p>Mariya V. Prismakova.</p><p>Moscow</p></bio><email xlink:type="simple">mirmariannka@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0167-4344</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алекберов</surname><given-names>Э. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekberov</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алекберов Эмиль Мушфигович.</p><p>Москва</p></bio><bio xml:lang="en"><p>Emil M. Alekberov.</p><p>Moscow</p></bio><email xlink:type="simple">alekberov.e.m@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3764-6131</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котов Сергей Владиславович — д-р мед. наук, профессор.</p><p>Москва</p></bio><bio xml:lang="en"><p>Sergey V. Kotov — Dr.Sc.(Med), Full Prof.</p><p>Moscow</p></bio><email xlink:type="simple">urokotov@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Городская клиническая больница № 1 им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University); Pirogov City Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Московский многопрофильный клинический центр «Коммунарка»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University); "Kommunarka" Moscow Multidisciplinary Clinical Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Городская клиническая больница им. В.М. Буянова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University); Buyanov City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова; Городская клиническая больница № 1 им. Н.И. Пирогова; Московский многопрофильный клинический центр «Коммунарка»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University); Pirogov City Clinical Hospital No. 1; "Kommunarka" Moscow Multidisciplinary Clinical Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>06</day><month>09</month><year>2024</year></pub-date><volume>12</volume><issue>4</issue><fpage>43</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ирицян М.М., Клименко А.А., Манцов А.А., Суюндиков И.К., Бут А.П., Рахматов Р.А., Присмакова М.В., Алекберов Э.М., Котов С.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ирицян М.М., Клименко А.А., Манцов А.А., Суюндиков И.К., Бут А.П., Рахматов Р.А., Присмакова М.В., Алекберов Э.М., Котов С.В.</copyright-holder><copyright-holder xml:lang="en">Iritsyan M.M., Klimenko A.A., Mantsov A.A., Suyundikov I.K., But A.P., Rakhmatov R.A., Prismakova M.V., Alekberov E.M., Kotov S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/919">https://www.urovest.ru/jour/article/view/919</self-uri><abstract><sec><title>Введение</title><p>Введение. Использование слизистой ротовой полости в аугментационной и заместительной уретропластике является золотым стандартом по ряду причин. Чаще всего используется слизистая щеки, нижней поверхности языка или губы. Оценка послеоперационных осложнений в области донорской зоны имеет важную роль, так как это влияет на качество жизни пациентов.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Оценить ранние и поздние послеоперационные изменения донорской зоны после забора графта ротовой полости для проведения уретропластики.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведён ретроспективный анализ результатов уретропластик с использованием слизистой ротовой полости с 2017 по 2022 год. В исследование включены 65 пациентов. Слизистую оболочку ротовой полости забирали с внутренней стороны щеки у 49 (75,38%) пациентов, с обеих внутренних сторон щёк — у 13 (20,0%), нижней губы — у 2 (3,07%) и нижней поверхности языка у — 1 (1,54%). Донорскую зону ушивали только в случае забора слизистой языка и губы. Интенсивность болевого синдрома в области забора графта пациенты оценивали по визуально-аналоговой шкале (ВАШ). Выполняли анализ функциональных и косметических характеристик донорской зоны.</p></sec><sec><title>Результаты</title><p>Результаты. В первые сутки послеоперационного периода медиана болевой симптоматики по ВАШ составила 4 [2 – 7] балла, на момент выписки — 3 [1 – 6] балла. На момент контрольного осмотра через 120 дней отмечен регресс болевой симптоматики: медиана ВАШ 0 [0 – 1] баллов. В позднем послеоперационном периоде зафиксировано: неполное открытие рта — у 2 (3,07%) пациентов, косметический дефект в области донорской зоны — у 2 (3,07%), неудобства во время приёма пищи — у 6 (9,23%), нарушение чувствительности в области донорской зоны — у 2 (3,07%), обострение хронического стоматита и гиперсаливация — у 2 (3,07%).</p></sec><sec><title>Заключение</title><p>Заключение. Частота осложнений в области донорской зоны достаточно низкая, но у некоторых пациентов это может привести к снижению качества жизни. Правильная техника забора графта слизистой ротовой полости снижает уровень болевого синдрома и вероятность развития ранних и поздних послеоперационных осложнений в этой зоне.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The use of oral mucosa in augmentation and replacement urethroplasty is the gold standard for several reasons. Most commonly, the mucous membrane of the cheek, the underside of the tongue or lip is employed. Assessing postoperative complications in the donor area is crucial as it impacts patients' quality of life.</p></sec><sec><title>Objective</title><p>Objective. To evaluate early and late postoperative changes in the donor area after oral graft extraction for urethroplasty</p></sec><sec><title>Materials &amp; methods</title><p>Materials &amp; methods. A retrospective analysis of the results of surgical treatment using oral mucosa from 2017 to 2022 was carried out. The study included 65 patients. The intensity of pain syndrome in the graft sampling area was assessed by patients on a visual analog scale (VAS). The donor area was sutured only in the case of tongue and lip mucosa sampling.</p></sec><sec><title>Results</title><p>Results. The mucous membrane of the oral cavity was harvested from different sites in 65 patients. Specifically, it was taken from the inside of the cheek in 49 patients (75.38%), from both inner sides of the cheeks in 13 (20.0%), the lower lip in two (3.07%) and the lower surface of the tongue in one (1.54%) patient, respectively. On the first day after surgery, the median pain level according to VAS was 4 points (range: 2 – 7), at the time of discharge — 3 points (1 – 6). After 120 days, a follow-up examination showed a regression of pain symptoms: the median was 0 points (0–1). In the late postoperative period, incomplete opening of the mouth was recorded in two patients (3.07%), cosmetic defect in the donor area in two (3.07%), discomfort during meals in six (9.23%), impaired sensitivity in the donor area in two (3.07%), exacerbation of chronic stomatitis and hypersalivation in two (3.07%) patients, respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. The incidence of complications in the donor area is low, but for some patients this can result in a reduced quality of life. Using proper technique when extracting oral mucosa grafts reduces pain and the likelihood of early- and late-stage postoperative complications in this area.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>стриктура уретры</kwd><kwd>уретропластика</kwd><kwd>слизистая полости рта</kwd></kwd-group><kwd-group xml:lang="en"><kwd>urethral stricture</kwd><kwd>urethroplasty</kwd><kwd>mouth mucosa</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Korneyev I, Ilyin D, Schultheiss D, Chapple C. The first oral mucosal graft urethroplasty was carried out in the 19th century: the pioneering experience of Kirill Sapezhko (1857-1928). Eur Urol. 2012;62(4):624-627. DOI: 10.1016/j.eururo.2012.06.035</mixed-citation><mixed-citation xml:lang="en">Korneyev I, Ilyin D, Schultheiss D, Chapple C. 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