<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2022-10-3-145-150</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-590</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Гигантская меланома полового члена</article-title><trans-title-group xml:lang="en"><trans-title>Giant penile melanoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2767-7153</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Валерьевич Попов — доктор медицинских наук, профессор; главный врач, руководитель городского центра эндоскопической урологии и новых технологий; профессор кафедры урологии</p><p>194044, Россия, г. Санкт-Петербург, ул. Чугунная, д. 46</p><p>194044, Россия, г. Санкт-Петербург, ул. Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>Sergey V. Popov — M.D., Dr.Sc. (Med), Full Prof.; Prof., Dept. of Urology, Kirov Military Medical Academy; Chief Medical Officer</p><p>46 Chugunnaya St., St. Petersburg, 194044, Russian Federation</p><p>37A Academician Lebedev St., St. Petersburg, 194044, Russian Federation</p></bio><email xlink:type="simple">doc.popov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5566-9789</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлов</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlov</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Игорь Николаевич Орлов — кандидат медицинских наук; заместитель главного врача по медицинской части; ассистент кафедры урологии</p><p>194044, Россия, г. Санкт-Петербург, ул. Чугунная, д. 46</p><p>191015, Россия, г. Санкт-Петербург, ул. Кирочная, д. 41</p></bio><bio xml:lang="en"><p>Igor N. Orlov — M.D., Cand.Sc.(Med); Head, Urology Division No.1, City Centre of Endoscopic Urology and New Technologies; Assist., Dept. of Urology</p><p>46 Chugunnaya St., St. Petersburg, 194044, Russian Federation</p><p>41 Kirochnaya St., St. Petersburg, 191015, Russian Federation</p></bio><email xlink:type="simple">doc.orlov@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8685-6525</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гринь</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Grin</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгений Александрович Гринь — врач-уролог отделения урологии №1 городского центра эндоскопической урологии и новых технологий</p><p>194044, Россия, г. Санкт-Петербург, ул. Чугунная, д. 46</p></bio><bio xml:lang="en"><p>Evgeny A. Grin — M.D., Urologist, Urology Division No.1, City Centre of Endoscopic Urology and New Technologies</p><p>46 Chugunnaya St., St. Petersburg, 194044, Russian Federation</p></bio><email xlink:type="simple">sv.lukaendouro@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5040-5546</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Топузов</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Topuzov</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимур Марленович Топузов — кандидат медицинских наук; заведующий отделением урологии №1 городского центра эндоскопической урологии и новых технологий</p><p>194044, Россия, г. Санкт-Петербург, ул. Чугунная, д. 46</p></bio><bio xml:lang="en"><p>Timur M. Topuzov — M.D., Cand.Sc. (Med); Urologist, Urology Division No.1, City Centre of Endoscopic Urology and New Technologies</p><p>46 Chugunnaya St., St. Petersburg, 194044, Russian Federation</p></bio><email xlink:type="simple">ttopuzov@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6169-2539</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цой</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsoy</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Валерьевич Цой — врач-уролог отделения урологии №1 городского центра эндоскопической урологии и новых технологий</p><p>194044, Россия, г. Санкт-Петербург, ул. Чугунная, д. 46</p></bio><bio xml:lang="en"><p>Alexey V. Tsoy — M.D.; Urologist, Urology Division No.1, City Centre of Endoscopic Urology and New Technologies</p><p>46 Chugunnaya St., St. Petersburg, 194044, Russian Federation</p></bio><email xlink:type="simple">alekseytsoy93@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3105-5947</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вязовцев</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vyazovtsev</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павел Вячеславович Вязовцев — кандидат медицинских наук; заведующий онкоурологическим отделением городского центра эндоскопической урологии и новых технологий</p><p>194044, Россия, г. Санкт-Петербург, ул. Чугунная, д. 46</p></bio><bio xml:lang="en"><p>Pavel V. Vyazovtsev — M.D., Cand.Sc.(Med); Head, Oncological Urology Division No.1, City Centre of Endoscopic Urology and New Technologies</p><p>46 Chugunnaya St., St. Petersburg, 194044, Russian Federation</p></bio><email xlink:type="simple">vpv.doc@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0469-7007</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернышева</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernysheva</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дарья Юрьевна Чернышева — кандидат медицинских наук; врач-уролог отделения урологии №1 городского центра эндоскопической урологии и новых технологий;; ассистент кафедры госпитальной хирургии медицинского факультета</p><p>194044, Россия, г. Санкт-Петербург, ул. Чугунная, д. 46</p><p>199034, Россия, г. Санкт-Петербург, Университетская наб., д. 7–9</p></bio><bio xml:lang="en"><p>Daria Yu. Chernysheva — M.D., Cand.Sc. (Med); Urologist, Urology Division No.1, City Centre of Endoscopic Urology and New Technologies</p><p>46 Chugunnaya St., St. Petersburg, 194044, Russian Federation</p><p>7-9 Universitetskaya Qy, St. Petersburg, 199034, Russian Federation</p></bio><email xlink:type="simple">daria.chern@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5336-8245</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котлов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotlov</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михаил Анатольевич Котлов — студент</p><p>191015, Россия, г. Санкт-Петербург, ул. Кирочная, д. 41</p></bio><bio xml:lang="en"><p>Mikhail A. Kotlov — Student</p><p>41 Kirochnaya St., St. Petersburg, 191015, Russian Federation</p></bio><email xlink:type="simple">kotlovm2013@yandex.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>СПб ГБУЗ «Клиническая больница Святителя Луки»; ФГБВОУ ВО «Военно-медицинская академия им. С.М. Кирова» Минобороны России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Luke St. Petersburg Clinical Hospital; Kirov Military Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СПб ГБУЗ «Клиническая больница Святителя Луки»; ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Luke St. Petersburg Clinical Hospital; Mechnikov North-Western State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>СПб ГБУЗ «Клиническая больница Святителя Луки»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Luke St. Petersburg Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>СПб ГБУЗ «Клиническая больница Святителя Луки»; ФГБОУ ВО «Санкт-Петербургский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Luke St. Petersburg Clinical Hospital; St. Petersburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mechnikov North-Western State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>2022</year></pub-date><volume>10</volume><issue>3</issue><fpage>145</fpage><lpage>150</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Попов С.В., Орлов И.Н., Гринь Е.А., Топузов Т.М., Цой А.В., Вязовцев П.В., Чернышева Д.Ю., Котлов М.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Попов С.В., Орлов И.Н., Гринь Е.А., Топузов Т.М., Цой А.В., Вязовцев П.В., Чернышева Д.Ю., Котлов М.А.</copyright-holder><copyright-holder xml:lang="en">Popov S.V., Orlov I.N., Grin E.A., Topuzov T.M., Tsoy A.V., Vyazovtsev P.V., Chernysheva D.Y., Kotlov M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/590">https://www.urovest.ru/jour/article/view/590</self-uri><abstract><p>Первичная меланома полового члена является чрезвычайно редкой казуистичной патологией, ассоциированной с неблагоприятным прогнозом. В статье представлен клинический случай массивного поражения полового члена меланомой, а также обсуждаются хирургические методы лечения данной патологии.</p></abstract><trans-abstract xml:lang="en"><p>Primary penile melanoma is an extremely rare casuistic pathology associated with a poor prognosis. The article presents a clinical case of massive lesion of the penis with malignant melanoma, and discusses surgical methods for treating this pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>меланома полового члена</kwd><kwd>хирургическое лечение</kwd><kwd>редкое новообразование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>penile melanoma</kwd><kwd>surgical treatment</kwd><kwd>rare neoplasm</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Iversen K, Robins RE. Mucosal malignant melanomas. Am J Surg. 1980;139(5):660-4. https://doi.org/10.1016/0002-9610(80)90358-x</mixed-citation><mixed-citation xml:lang="en">Iversen K, Robins RE. Mucosal malignant melanomas. Am J Surg. 1980;139(5):660-4. https://doi.org/10.1016/0002-9610(80)90358-x</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sánchez-Ortiz R, Huang SF, Tamboli P, Prieto VG, Hester G, Pettaway CA. Melanoma of the penis, scrotum and male urethra: a 40-year single institution experience. J Urol. 2005;173(6):1958-65. https://doi.org/10.1097/01.ju.0000159207.91737.53</mixed-citation><mixed-citation xml:lang="en">Sánchez-Ortiz R, Huang SF, Tamboli P, Prieto VG, Hester G, Pettaway CA. Melanoma of the penis, scrotum and male urethra: a 40-year single institution experience. J Urol. 2005;173(6):1958-65. https://doi.org/10.1097/01.ju.0000159207.91737.53</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Franceschelli A, Palmisano F, Gentile G, Vagnoni V, Zannetti G, Cipriani R, Colombo F. Melanoma of glans penis and urethra: A case report and systematic review of the literature of a rare and complex neoplasm. Urologia. 2021:3915603211046471. https://doi.org/10.1177/03915603211046471</mixed-citation><mixed-citation xml:lang="en">Franceschelli A, Palmisano F, Gentile G, Vagnoni V, Zannetti G, Cipriani R, Colombo F. Melanoma of glans penis and urethra: A case report and systematic review of the literature of a rare and complex neoplasm. Urologia. 2021:3915603211046471. https://doi.org/10.1177/03915603211046471</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">van Geel AN, den Bakker MA, Kirkels W, Horenblas S, Kroon BB, de Wilt JH, Eggermont AM, Mooi WJ, van der Aa MN. Prognosis of primary mucosal penile melanoma: a series of 19 Dutch patients and 47 patients from the literature. Urology. 2007;70(1):143-7. https://doi.org/10.1016/j.urology.2007.03.039</mixed-citation><mixed-citation xml:lang="en">van Geel AN, den Bakker MA, Kirkels W, Horenblas S, Kroon BB, de Wilt JH, Eggermont AM, Mooi WJ, van der Aa MN. Prognosis of primary mucosal penile melanoma: a series of 19 Dutch patients and 47 patients from the literature. Urology. 2007;70(1):143-7. https://doi.org/10.1016/j.urology.2007.03.039</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Coit DG, Thompson JA, Albertini MR, Barker C, Carson WE, Contreras C, Daniels GA, DiMaio D, Fields RC, Fleming MD, Freeman M, Galan A, Gastman B, Guild V, Johnson D, Joseph RW, Lange JR, Nath S, Olszanski AJ, Ott P, Gupta AP, Ross MI, Salama AK, Skitzki J, Sosman J, Swetter SM, Tanabe KK, Wuthrick E, McMillian NR, Engh AM. Cutaneous Melanoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019;17(4):367-402. https://doi.org/10.6004/jnccn.2019.0018</mixed-citation><mixed-citation xml:lang="en">Coit DG, Thompson JA, Albertini MR, Barker C, Carson WE, Contreras C, Daniels GA, DiMaio D, Fields RC, Fleming MD, Freeman M, Galan A, Gastman B, Guild V, Johnson D, Joseph RW, Lange JR, Nath S, Olszanski AJ, Ott P, Gupta AP, Ross MI, Salama AK, Skitzki J, Sosman J, Swetter SM, Tanabe KK, Wuthrick E, McMillian NR, Engh AM. Cutaneous Melanoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019;17(4):367-402. https://doi.org/10.6004/jnccn.2019.0018</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Pandey M, Mathew A, Abraham EK, Ahamed IM, Nair KM. Primary malignant melanoma of the mucous membranes. Eur J Surg Oncol. 1998;24(4):303-7. https://doi.org/10.1016/s0748-7983(98)80011-5</mixed-citation><mixed-citation xml:lang="en">Pandey M, Mathew A, Abraham EK, Ahamed IM, Nair KM. Primary malignant melanoma of the mucous membranes. Eur J Surg Oncol. 1998;24(4):303-7. https://doi.org/10.1016/s0748-7983(98)80011-5</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Rogers RS 3rd, Gibson LE. Mucosal, genital, and unusual clinical variants of melanoma. Mayo Clin Proc. 1997;72(4):362-6. https://doi.org/10.4065/72.4.362</mixed-citation><mixed-citation xml:lang="en">Rogers RS 3rd, Gibson LE. Mucosal, genital, and unusual clinical variants of melanoma. Mayo Clin Proc. 1997;72(4):362-6. https://doi.org/10.4065/72.4.362</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Papeš D, Altarac S, Arslani N, Rajković Z, Antabak A, Ćaćić M. Melanoma of the glans penis and urethra. Urology. 2014;83(1):6-11. https://doi.org/10.1016/j.urology.2013.07.009</mixed-citation><mixed-citation xml:lang="en">Papeš D, Altarac S, Arslani N, Rajković Z, Antabak A, Ćaćić M. Melanoma of the glans penis and urethra. Urology. 2014;83(1):6-11. https://doi.org/10.1016/j.urology.2013.07.009</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbé C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-23. https://doi.org/10.1056/NEJMoa1003466</mixed-citation><mixed-citation xml:lang="en">Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbé C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-23. https://doi.org/10.1056/NEJMoa1003466</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
