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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2022-10-3-74-83</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-583</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Экспериментальное обоснование нефрорафии</article-title><trans-title-group xml:lang="en"><trans-title>Experimental substantiation of kidney sutures</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2495-5760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шкодкин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shkodkin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Валентинович Шкодкин — доктор медицинских наук, доцент; профессор кафедры госпитальной хирургии Медицинского института; врач-уролог урологического отделения</p><p>308015, Россия, г. Белгород, ул. Победы, д. 85</p><p>308007, Россия, г. Белгород, ул. Некрасова, д. 8/9</p></bio><bio xml:lang="en"><p>Sergey V. Shkodkin — M.D., Dr.Sc.(Med), Assoc.Prof.(Docent); Prof., Dept. of Advanced Surgery, Medical Institute; Urologist</p><p>85 Victory St., Belgorod, 308015, Russian Federation</p><p>8/9 Nekrasova St., Belgorod, 308007, Russian Federation</p></bio><email xlink:type="simple">shkodkin-s@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2318-9494</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Идашкин</surname><given-names>Ю. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Idashkin</surname><given-names>Yu. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Борисович Идашкин — врач-уролог урологического отделения</p><p>308007, Россия, г. Белгород, ул. Некрасова, д. 8/9</p></bio><bio xml:lang="en"><p>Yury B. Idashkin — M.D.; Urologist</p><p>8/9 Nekrasova St., Belgorod, 308007, Russian Federation</p></bio><email xlink:type="simple">shkodkin-s@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4048-3986</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубайди</surname><given-names>М. З. А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zubaidi</surname><given-names>M. Z. A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мохаммедейн Захран Абед Альфаттах Зубаиди — аспирант кафедры госпитальной хирургии Медицинского института</p><p>308015, Россия, г. Белгород, ул. Победы, д. 85</p></bio><bio xml:lang="en"><p>Mohammedain Z. A. A. Zubaydi — M.D.; Postgraduate student, Dept. of Advanced Surgery, Medical Institute</p><p>85 Victory St., Belgorod, 308015, Russian Federation</p></bio><email xlink:type="simple">zubaydi@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9813-9523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кравец</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kravets</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анатолий Дмитриевич Кравец — кандидат медицинских наук; врач-уролог урологического отделения</p><p>450071, Россия, г. Уфа, Лесной проезд, д. 3</p></bio><bio xml:lang="en"><p>Аnatoly D. Kravets — M.D., Cand.Sc.(Med); Urologist, Urology Division</p><p>3 Lesnoy Dr., Ufa, 450071, Russian Federation</p></bio><email xlink:type="simple">kranatolius@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9869-7376</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хусейнзода</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Khuseinzoda</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абдуллои Файзали Хусейнзода — аспирант кафедры госпитальной хирургии Медицинского института</p><p>308015, Россия, г. Белгород, ул. Победы, д. 85</p></bio><bio xml:lang="en"><p>Abdulloi F. Huseynzoda — M.D.; Postgraduate student, Dept. of Advanced Surgery</p><p>85 Victory St., Belgorod, 308015, Russian Federation</p></bio><email xlink:type="simple">husenzoda.abdullo@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0686-9693</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аскари</surname><given-names>Ж. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Askari</surname><given-names>Zh. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жехад Кхалил Аскари — аспирант кафедры госпитальной хирургии Медицинского института</p><p>308015, Россия, г. Белгород, ул. Победы, д. 85</p></bio><bio xml:lang="en"><p>Jehad K. Askari — M.D.; Postgraduate student, Dept. of Advanced Surgery, Medical Institute</p><p>85 Victory St., Belgorod, 308015, Russian Federation</p></bio><email xlink:type="simple">dr_askari@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0811-681X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарев</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomarev</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгений Геннадьевич Пономарев — ординатор кафедры госпитальной хирургии Медицинского института</p><p>308015, Россия, г. Белгород, ул. Победы, д. 85</p></bio><bio xml:lang="en"><p>Evgeniy G. Ponomarev — Resident, Dept. of Advanced Surgery</p><p>85 Victory St., Belgorod, 308015, Russian Federation</p></bio><email xlink:type="simple">dr.ponomarev95@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5726-5945</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нечипоренко</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Nechiporenko</surname><given-names>V. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владислав Юрьевич Нечипоренко — ординатор кафедры госпитальной хирургии Медицинского института</p><p>308015, Россия, г. Белгород, ул. Победы, д. 85</p></bio><bio xml:lang="en"><p>Vladislav Y. Nechiporenko — Resident, Dept. of Advanced Surgery</p><p>85 Victory St., Belgorod, 308015, Russian Federation</p></bio><email xlink:type="simple">nechiporenko@bsu.edu.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4270-165X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шкодкин</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shkodkin</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кирилл Сергеевич Шкодкин — ординатор кафедры госпитальной хирургии Медицинского института</p><p>308015, Россия, г. Белгород, ул. Победы, д. 85</p></bio><bio xml:lang="en"><p>Kirill S. Shkodkin — Resident, Dept. of Advanced Surgery</p><p>85 Victory St., Belgorod, 308015, Russian Federation</p></bio><email xlink:type="simple">kirill_shkodkin@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Белгородский государственный национальный исследовательский университет» Минобрнауки России; ОГБУЗ «Белгородская областная клиническая больница Святителя Иоасафа»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Belgorod State National Research University; St. Joasaph Belgorod Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ОГБУЗ «Белгородская областная клиническая больница Святителя Иоасафа»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Joasaph Belgorod Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Белгородский государственный национальный исследовательский университет» Минобрнауки России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Belgorod State National Research University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ РБ «Городская клиническая больница №21 г. Уфы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ufa City Clinical Hospital No. 21</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>2022</year></pub-date><volume>10</volume><issue>3</issue><fpage>74</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шкодкин С.В., Идашкин Ю.Б., Зубайди М.З., Кравец А.Д., Хусейнзода А.Ф., Аскари Ж.К., Пономарев Е.Г., Нечипоренко В.Ю., Шкодкин К.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Шкодкин С.В., Идашкин Ю.Б., Зубайди М.З., Кравец А.Д., Хусейнзода А.Ф., Аскари Ж.К., Пономарев Е.Г., Нечипоренко В.Ю., Шкодкин К.С.</copyright-holder><copyright-holder xml:lang="en">Shkodkin S.V., Idashkin Y.B., Zubaidi M.Z., Kravets A.D., Khuseinzoda A.F., Askari Z.K., Ponomarev E.G., Nechiporenko V.Y., Shkodkin K.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/583">https://www.urovest.ru/jour/article/view/583</self-uri><abstract><sec><title>Введение</title><p>Введение. Резекция почки по праву занимает приоритетное положение в лечении локализованного почечно-клеточного рака. Она не только обеспечивает высокие онкологические результаты, но и позволяет сохранить почечную паренхиму, снижая тем самым риск хронической болезни почек и кардиоваскулярных катастроф, что особенно актуально у молодых пациентов. Основной технической проблемой, особенно у пациентов с большими эндофитными образованиями, является закрытие почечной раны с обеспечением надёжного гемостаза и низкого риска подтекания мочи.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Изучить в экспериментальных условиях механические свойства почечной паренхимы и обосновать способы предупреждения прорезывания шва.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Исследования выполнены с использованием оборудования Центра коллективного пользования «Технологии и материалы НИУ БелГУ». Механические испытания прочностных характеристик слоёв почечной паренхимы выполнены на секционном материале 60 кадаверных почек. На разрывной машине изучены предел прочности и напряжение в тканях при наложении различных швов, а также варианты последних с использованием прокладок из материалов, предупреждающих прорезывание нити.</p></sec><sec><title>Результаты</title><p>Результаты. При проведении механических испытаний установлено, что наибольшей прочностью среди слоёв почечной паренхимы обладает мозговое вещество — 23,58 ± 9,17 Н. Механическая прочность коркового вещества в отсутствии капсулы была минимальной — 8,4 ± 2,89 Н. Замена вертикального шва через все слои с завязыванием узла по линии резекции на аналогичный горизонтальный матрацный шов статистически достоверно повышала предел прочности до уровней, сопоставимых с пределом прочности мозгового вещества — 27,35 ± 12,04 Н. Применение в качестве прокладки гемостатической сетки (SurgicelÒ) значимо не влияло на предел прочности горизонтального матрацного шва — 23,58 ± 9,17 Н. Использование с этой целью проленовой сетки (LintexÒ) достоверно предотвращало прорезывание шва по сравнению с нативным швом и сеткой SurgicelÒ 31,48 ± 9,98 Н. Максимальные показатели предела прочности горизонтального матрацного шва были получены для ленты из политетрафторэтиленового сосудистого протеза — 45,61 ± 6,1 Н.</p></sec><sec><title>Заключение</title><p>Заключение. Исследование механической прочности слоёв почечной паренхимы показало нецелесообразность выполнения кортикального шва. Использование горизонтального матрацного шва достоверно повышает предел прочности по сравнению с вертикальным. Максимальные механические прочностные характеристики были получены при применении прокладок из политетрафторэтилена.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Partial nephrectomy occupies a rightful priority position in the treatment of localized renal cell carcinoma. It not only provides high oncological results but also allows you to save the renal parenchyma. This reduces the risk of chronic kidney disease and cardiovascular accidents, which is especially important in young patients. The main technical problem is the closure of the renal wound with reliable hemostasis and low risk of urine leakage, especially in patients with large endophytic lesions.</p></sec><sec><title>Objective</title><p>Objective. To study the mechanical properties of the renal parenchyma and to establish ways to prevent suture eruption under an experimental model.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The studies were carried out using the equipment of the Center for Collective Use "Technologies and Materials of the Belgorod State National Research University". Mechanical tests of the strength characteristics of the layers of the renal parenchyma were performed on 60 cadaveric kidneys. The tensile strength and tension of tissues during the application of various surgical sutures, as well as variants of the latter with the use of spacers made of materials that prevent thread eruption, were studied using a tensile machine.</p></sec><sec><title>Results</title><p>Results. During mechanical tests, the medulla was found to have the highest strength (23.58 ± 9.17 load (L)) between the layers of the renal parenchyma. The mechanical strength (8.40 ± 2.89 L) of the cortical substance in the absence of the capsule was minimal. When replacing the vertical suture through all layers by tied a knot along the resection line with a similar horizontal mattress suture, it significantly increased tensile strength (27.35 ± 12.04 L) to levels comparable to the tensile strength of the medulla. The use of a hemostatic mesh (SurgicelÒ) as a lining did not significantly affect the ultimate strength (23.58 ± 9.17 L) of the horizontal mattress suture. The use of a prolene mesh (LintexÒ mesh) for this purpose significantly prevented suture eruption (31.48 ± 9.98 L) compared to the native suture and the SurgicelÒ mesh. The maximum tensile strength (45.61 ± 6.1 L) of a horizontal mattress suture was obtained for a tape made of a polytetrafluoroethylene vascular prosthesis.</p></sec><sec><title>Conclusion</title><p>Conclusion. The study of the mechanical strength of the layers of the renal parenchyma showed the inexpediency of performing a cortical suture. The use of a horizontal mattress suture significantly increases the tensile strength compared to a vertical one. Maximum mechanical strength characteristics were obtained using polytetrafluoroethylene inserts.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>резекция почки</kwd><kwd>нефрорафия</kwd><kwd>шов почки</kwd><kwd>прочность тканей</kwd><kwd>нефронсберегающая хирургия</kwd><kwd>кровотечение</kwd><kwd>геморрагические осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>partial nephrectomy</kwd><kwd>nephrorrhaphy</kwd><kwd>kidney suture</kwd><kwd>tissue strength</kwd><kwd>nephron-sparing surgery</kwd><kwd>bleeding</kwd><kwd>hemorrhagic complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">MacLennan S, Imamura M, Lapitan MC, Omar MI, Lam TB, Hilvano-Cabungcal AM, Royle P, Stewart F, MacLennan G, MacLennan SJ, Dahm P, Canfield SE, McClinton S, Griffiths TR, Ljungberg B, N'Dow J. 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