urovestВестник урологииUrology Herald2308-6424Rostov State Medical University10.21886/2308-6424-2020-8-2-99-106urovest-335Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWS ARTICLEОбъём-образующие вещества в лечении стрессового недержания мочи у женщинBulking agents in case of treatment of female stress urinary incontinencehttps://orcid.org/0000-0002-3497-5856ЦукановА. Ю.TsukanovA. Yu.

Антон Юрьевич Цуканов ‒ д.м.н., профессор; заведующий кафедрой хирургических болезней и урологии ДПО 

тел.: +7 (913) 967-36-76

Anton Yu. Tsukanov – M.D., Dr.Sc.(M), Full Prof.; Head, Dept. of Surgery and Urology

tel.: +7 (913) 967-36-76

autt@mail.ruhttps://orcid.org/0000-0001-8729-4731МирзакадиевА. А.MirzakadievA. A.

Арсен Абдусаламович Мирзакадиев ‒ аспирант кафедры хирургических болезней и урологии ДПО

Arsen A. Mirzakadiev – M.D., Postgrad. Student, Dept. of Surgery and Urology,

dr.arst@inbox.ruhttps://orcid.org/0000-0001-7345-7245ДункурсА. В.DunkursA. V.

Артём Владимирович Дункурс ‒ ординатор кафедры хирургических болезней и урологии ДПО

Artem V. Dunkurs – Resident, Dept. of Surgery and Urology

dunkurs_av@mail.ruФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииРоссияOmsk State Medical UniversityRussian Federation2020010720208299106Copyright © Цуканов А.Ю., Мирзакадиев А.А., Дункурс А.В., 20202020Цуканов А.Ю., Мирзакадиев А.А., Дункурс А.В.Tsukanov A.Y., Mirzakadiev A.A., Dunkurs A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.urovest.ru/jour/article/view/335

Основным методом лечения стрессового недержания мочи является хирургический. В последние годы этот подход к лечению оказался под пристальным вниманием и подвергается переоценке в связи с пересмотром баланса риска и выгоды для пациентки. Одним из вариантов оказания помощи женщинам с нетяжёлым и неосложнённым недержанием мочи при напряжении является введение объём-образующих веществ, позволяющее достичь эффекта через коаптацию мочеиспускательного канала. Известны различные типы веществ: твёрдые микрочастицы в абсорбируемом жидком или гелевом носителе, носители, содержащие трудно адсорбируемый гомогенный гель (без частиц). Описаны и различные способы введения объём-образующих веществ: трансуретральный и субуретральный с расположением импланта в подслизистом слое уретры, под ней, а также вокруг органа. Различные авторы предлагают и различный контроль имплантации — эндоскопический и посредством ультразвукового исследования. В обзоре рассматриваются доступные в настоящее время объём-образующие вещества, методы применения, эффективность и известные осложнения. Кроме того, предложен авторский оригинальный способ введения объём-образующего вещества и приведены первые результаты его применения.

The main treatment for stress urinary incontinence is surgical. However, this approach to treatment has come under scrutiny and is undergoing reevaluation in connection with the revision of the balance of risk and benefit for the patient in recent years. Increasingly, the introduction of volume-forming substances as a method of alternative care for women with mild and uncomplicated urinary incontinence during exercise is being discussed. This treatment option achieves the effect through coaptation of the urethra. Various types of substances are known solid microparticles in an absorbable liquid or gel carrier, carriers containing a hard-to-absorb homogeneous gel (without particles). Separate methods of introducing volume-forming substances are also described: transurethral and suburethral with the location of the implant in the submucous layer of the urethra, under it, and around the organ. Various authors suggest different implantation control: endoscopic and under ultrasound guidance. The review discusses the currently available volumeforming substances, methods of use, effectiveness and known complications. Besides, an original method of injection a volume-forming substance is proposed, and the first results of its application are presented.

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The authors declare that there are no conflicts of interest present.