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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2018-6-4-5-12</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-230</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Клиническая роль гиперкинезов сфинктера уретры при лечении доброкачественной гиперплазии простаты</article-title><trans-title-group xml:lang="en"><trans-title>The clinical signifi cance of urethral sphincter hyperkinesis in the treatment of benign prosta???? c hyperplasia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0674-9429</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоусов</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Belousov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белоусов Игорь Иванович – д.м.н., доцент; профессор кафедры урологии и репродуктивного здоровья человека с курсом детской урологии–андрологии.</p><p>Ростов-на-Дону.</p></bio><bio xml:lang="en"><p>Igor I. Belousov – MD, PhD (M), DMS, Associate Professor (Docent); Professor, Department of Urology and Human Reproductive Health with the course of Pediatric Urologyandrology, Rostov State Medical University.</p><p>Rostov-on-Don.</p></bio><email xlink:type="simple">belrost_dept@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ростовский государственный медицинский университет» МЗ РФ.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>21</day><month>02</month><year>2019</year></pub-date><volume>6</volume><issue>4</issue><fpage>5</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белоусов И.И., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Белоусов И.И.</copyright-holder><copyright-holder xml:lang="en">Belousov I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/230">https://www.urovest.ru/jour/article/view/230</self-uri><abstract><p>Актуальность. Несмотря на существующее многообразие высокоэффективных хирургических подходов в лечении доброкачественной гиперплазии простаты (ДГПЖ) и внедрение новых технологий у части пациентов результаты оперативного лечения в краткосрочном и долгосрочном плане оказываются неудовлетворительными.Цель исследования. Повышение эффективности результатов лечения пациентов с доброкачественной гиперплазией предстательной железы.Материалы и методы. Изучено функциональное состояние уретрального сфинктера у 123 больных с симптомной ДГПЖ. Соответственно методу лечения все пациенты были разделены на группы. 1-я группа – больные с установленными стандартными показаниями к оперативному лечению. После операции пациентам с сохраняющимся обструктивным мочеиспусканием проведена терапия миорелаксантом центрального действия в течение трех месяцев. 2 группа - пациенты с неосложненной ДГПЖ, имеющие гипертонус уретрального сфинктера и получавшие медикаментозную терапию соответственно установленным уродинамическим паттернамРезультаты. Анализ собственных результатов эффективности оперативного лечения пациентов с ДГПЖ показывает наличие статистически значимой связи негативных результатов хирургии ДГПЖ с повышением тонуса наружного уретрального сфинктера. В 70,1% наблюдений клинически выраженные обструктивные симптомы нижних мочевых путей (СНМП) при ДГПЖ сопровождаются гипертонусом уретрального сфинктера, что, возможно, связано с анатомическими характеристиками узлов гиперплазии.Выводы. В 14,5% случаев нарушения функции уретрального сфинктера обусловливают неудовлетворительный эффект оперативного лечения ДГПЖ. Проведение в этих случаях фармакотерапии миорелаксантами центрального действия достоверно улучшает уродинамику нижних мочевых путей, что сопровождается регрессом СНМП.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. Today there is many highly effective surgical approaches in the treatment of benign prostatic hyperplasia (BPH). New technologies in the treatment of BPH continue to be implemented. Despite this in some patients the results of surgical treatment for short-term and long-term monitoring is unsatisfactory.Purpose of research. Тo improve the results of treatment of patients with benign prostatic hyperplasiaMaterials and methods. The functional state of the urethral sphincter was studied in 123 patients with symptomatic BPH. According to the treatment method, all patients were separated into groups. Group 1 - patients with established standard indications for surgical treatment. After surgery, patients with persistent obstructive urination received therapy with a central muscle relaxant for three months. Group 2 - patients with uncomplicated BPH, having hypertonic urethral sphincter and receiving drug therapy according to the established urodynamic patterns.Results. Our analysis of the efficacy of surgical treatment of patients with BPH demonstrates a significant correlation between negative outcomes of surgery for BPH with increased tone of the external urethral sphincter. So, in 70.1% of cases, symptomatic obstructive Low Urinary Tract Symptoms (LUTS) in BPH were accompanied by increased tone of the urethral sphincter from standard parameters. We believe that these changes were related to the anatomical characteristics of nodular hyperplasia.Conclusions. Exactly this fact, that these patients had urethral sphincter dysfunction in 14.5% of cases made for poor effect of surgical treatment of BPH. Use of muscle relaxants centrally acting drug therapy in these cases, significantly improves the urodynamics of lower urinary tract, which is accompanied by regression of LUTS.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>симптомы нижних мочевых путей</kwd><kwd>доброкачественная гиперплазия простаты</kwd><kwd>сфинктер уретры</kwd><kwd>лекарственная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>low urinary tract symptoms</kwd><kwd>benign prostatic hyperplasia</kwd><kwd>urethral sphincter</kwd><kwd>drug therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Deering RE, Bigler SA, King J. Choongkittaworn M, Aramburu E, Brawer MK. Morphometric quantitation of stroma in human benign prostatic hyperplasia. Urology. 1994;44(1):64-70. PMID: 7518983</mixed-citation><mixed-citation xml:lang="en">Deering RE, Bigler SA, King J. 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