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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2018-6-1-48-54</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-191</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS ARTICLE</subject></subj-group></article-categories><title-group><article-title>ВАКУУМ ИНДУЦИРОВАННАЯ ЭРЕКЦИЯ – ПРОФИЛАКТИКА ГИПОКСИИ КАВЕРНОЗНОЙ ТКАНИ У ПАЦИЕНТОВ ПОСЛЕ РАДИКАЛЬНОЙ ПРОСТАТЭКТОМИИ</article-title><trans-title-group xml:lang="en"><trans-title>VACUUM THERAPY – PREVENTION OF HYPOXIA OF CAVERNOUS TISSUE PATIENTS AFTER RADICAL PROSTATECTOMY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2892-5665</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осадчинский</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Osadchinskii</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ведущий специалист Управления организации стационарной медицинской помощи,</p><p>Москва</p></bio><bio xml:lang="en"><p>Chief specialist of Management of the organization of inpatient medical care,</p><p>Moscow</p></bio><email xlink:type="simple">osadchinskiy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7469-3952</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виноградов</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinogradov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой клинической андрологии ФПКМР,</p><p>Москва</p></bio><bio xml:lang="en"><p>DM, Professor, Head of the Department of Clinical Andrology,</p><p>Moscow</p></bio><email xlink:type="simple">ivvinogradov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3797-7160</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Даренков</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Darenkov</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой урологии,</p><p>Москва</p></bio><bio xml:lang="en"><p>MD, Professor, Head of the Department of Urology,</p><p>Moscow</p></bio><email xlink:type="simple">darenkov@list.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Департамент здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Health of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ ДПО «ЦГМА»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of department of presidential affairs</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2018</year></pub-date><volume>6</volume><issue>1</issue><fpage>48</fpage><lpage>54</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Осадчинский А.Е., Виноградов И.В., Даренков С.П., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Осадчинский А.Е., Виноградов И.В., Даренков С.П.</copyright-holder><copyright-holder xml:lang="en">Osadchinskii A.E., Vinogradov I.V., Darenkov S.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/191">https://www.urovest.ru/jour/article/view/191</self-uri><abstract><p>Пациенты, перенесшие радикальную простатэктомию с применением нервосберегающей техники по поводу рака предстательной железы без проведения соответствующей программы пенильной реабилитации в послеоперационном периоде, подвержены риску формирования кавернозного фиброза с возникновением последующей стойкой эректильной дисфункции. С целью минимизации повреждения кавернозной ткани и раннего восстановления эректильной функции во время периода нейропраксии необходимо обеспечение достаточного уровня оксигенации. Роль применения вакуума в пенильной реабилитации для профилактики гипоксии кавернозной ткани до конца не ясна из-за отсутствия данных о газовом составе крови в момент достижения вакуум-индуцированной эрекции. Целью данной работы являлся обзор научных исследований, посвященных изучению вакуум-индуцированной эрекции полового члена на животных или людях, свидетельствующий о высоких результатах за счет увеличения оксигенации кавернозной ткани.</p></abstract><trans-abstract xml:lang="en"><p>Patients, after radical prostatectomy with the use of nerve-sparing techniques, without carrying out penile rehabilitation, are at risk of forming cavernous fibrosis with the emergence of subsequent persistent erectile dysfunction. In order to minimize damage to cavernous tissue and early restoration of erectile function during the period of neuropraxia, it is necessary to ensure a sufficient level of oxygenation. The role of applying vacuum in penile rehabilitation for the prevention of hypoxia of cavernous tissue is not fully understood, due to the lack of data on the gaseous composition of the blood at the time of reaching the vacuum of erection. The purpose of this work was to review the scientific studies devoted to the study of vacuum induced penile erection in animals or humans, which indicates high results due to increased oxygenation of cavernous tissue.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гипоксия кавернозной ткани</kwd><kwd>пенильная реабилитация</kwd><kwd>вакуум индуцированная эрекция</kwd><kwd>эректильная дисфункция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>phypoxia of cavernous tissue</kwd><kwd>penile rehabilitation</kwd><kwd>vacuum erector device</kwd><kwd>erectile dysfunction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sheng-Qiang Q, Liang G, Qiang W, Jiuhong Y. Vacuum therapy in penile rehabilitation atier radical prostatectomy: review of hemodynamic and antihypoxic evidence. Asian Journal of Andrology. 2016;18:446-451. doi: 10.4103/1008-682X.159716</mixed-citation><mixed-citation xml:lang="en">Sheng-Qiang Q, Liang G, Qiang W, Jiuhong Y. Vacuum therapy in penile rehabilitation atier radical prostatectomy: review of hemodynamic and antihypoxic evidence. Asian Journal of Andrology. 2016;18:446-451. doi: 10.4103/1008-682X.159716</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Welliver R, Mechlin C, Goodwin B, Alukal J, McCullough A. A pilot study to determine penile oxygen saturation before and atier vacuum therapy in patients with erectile dysfunction atier radical prostatectomy. J Sex Med. 2014;11:1071-7. doi:10.1111/jsm.12445</mixed-citation><mixed-citation xml:lang="en">Welliver R, Mechlin C, Goodwin B, Alukal J, McCullough A. A pilot study to determine penile oxygen saturation before and atier vacuum therapy in patients with erectile dysfunction atier radical prostatectomy. J Sex Med. 2014;11:1071-7. doi:10.1111/jsm.12445</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kim N, Vardi Y, Padma-Nathan H, Daley J, Goldstein I, Saenz de Tejada I. Oxygen tension regulates the nitric oxide pathway. Physiological role in penile erection. J Clin Invest. 1993;91:437. doi:10.1172/JCI116220</mixed-citation><mixed-citation xml:lang="en">Kim N, Vardi Y, Padma-Nathan H, Daley J, Goldstein I, Saenz de Tejada I. Oxygen tension regulates the nitric oxide pathway. Physiological role in penile erection. J Clin Invest. 1993;91:437. doi:10.1172/JCI116220</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Fisher C, Gross J, Zuch J. Cycle of penile erection synchronous with dreaming (REM) sleep: preliminary report. Arch Gen Psychiatry. 1965;12:29-45. doi: 10.1001/archpsyc.1965.01720310031005</mixed-citation><mixed-citation xml:lang="en">Fisher C, Gross J, Zuch J. Cycle of penile erection synchronous with dreaming (REM) sleep: preliminary report. Arch Gen Psychiatry. 1965;12:29-45. doi: 10.1001/archpsyc.1965.01720310031005</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Moreland R. Is there a role of hypoxemia in penile brosis: a viewpoint presented to the Society for the Study of Impotence. Int J Impot Res. 1998;10:113-20. doi:10.1038/ sj.ijir.3901042</mixed-citation><mixed-citation xml:lang="en">Moreland R. Is there a role of hypoxemia in penile brosis: a viewpoint presented to the Society for the Study of Impotence. Int J Impot Res. 1998;10:113-20. doi:10.1038/ sj.ijir.3901042</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mulhall J, Morgentaler A. Controversies in sexual medicine: penile rehabilitation should become the norm for radical prostatectomy patients. J Sex Med. 2007;4:538- 43. doi: 10.21037/tau.2016.08.14</mixed-citation><mixed-citation xml:lang="en">Mulhall J, Morgentaler A. Controversies in sexual medicine: penile rehabilitation should become the norm for radical prostatectomy patients. J Sex Med. 2007;4:538- 43. doi: 10.21037/tau.2016.08.14</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hakky T, Baumgarten A, Parker J, Zheng Y, Kongnyuy M, Martinez D, Carrio R. Penile Rehabilitation: The Evolutionary Concept in the Management of Erectile Dysfunction. Current Urology Reports. 2014;15(4):393. doi: 10.1007/s11934-014-0393-6</mixed-citation><mixed-citation xml:lang="en">Hakky T, Baumgarten A, Parker J, Zheng Y, Kongnyuy M, Martinez D, Carrio R. Penile Rehabilitation: The Evolutionary Concept in the Management of Erectile Dysfunction. Current Urology Reports. 2014;15(4):393. doi: 10.1007/s11934-014-0393-6</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Teloken P, Mesquita G, Montorsi F, Mulhall J. Post-radical prostatectomy pharmacological penile rehabilitation: practice patierns among the international society for sexual medicine practitioners. J Sex Med. 2009;6:2032-8. doi: 10.1111/j.1743-6109.2009.01269.x.</mixed-citation><mixed-citation xml:lang="en">Teloken P, Mesquita G, Montorsi F, Mulhall J. Post-radical prostatectomy pharmacological penile rehabilitation: practice patierns among the international society for sexual medicine practitioners. J Sex Med. 2009;6:2032-8. doi: 10.1111/j.1743-6109.2009.01269.x.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Tal R, Teloken P, Mulhall J. Erectile function rehabilitation atier radical prostatectomy: practice paƩ erns among AUA members. J Sex Med. 2011;8:2370-6. doi: 10.1111/j.1743-6109.2011.02355.x</mixed-citation><mixed-citation xml:lang="en">Tal R, Teloken P, Mulhall J. Erectile function rehabilitation atier radical prostatectomy: practice paƩ erns among AUA members. J Sex Med. 2011;8:2370-6. doi: 10.1111/j.1743-6109.2011.02355.x</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Lin H, Wang G, Wang R. Vacuum erectile device for penile rehabilitation. J Integr Nephrol Androl. 2014;1:4-10. doi: 10.4103/2225-1243.137541</mixed-citation><mixed-citation xml:lang="en">Lin H, Wang G, Wang R. Vacuum erectile device for penile rehabilitation. J Integr Nephrol Androl. 2014;1:4-10. doi: 10.4103/2225-1243.137541</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bosshardt R, Farwerk R, Sikora R, Sohn M, Jakse G. Objective measurement of the effectiveness, therapeutic success and dynamic mechanisms of the vacuum device. Brit J Urol. 1995;75:786-791. doi: 10.1111/j.1464- 410X.1995.tb07392.x</mixed-citation><mixed-citation xml:lang="en">Bosshardt R, Farwerk R, Sikora R, Sohn M, Jakse G. Objective measurement of the effectiveness, therapeutic success and dynamic mechanisms of the vacuum device. Brit J Urol. 1995;75:786-791. doi: 10.1111/j.1464- 410X.1995.tb07392.x</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Padmanabhan P, McCullough A. Penile oxygen saturation in the fl accid and erect penis in men with and without erectile dysfunction. J Androl. 2007;28:223-8. doi:10.2164/jandrol.106.001313</mixed-citation><mixed-citation xml:lang="en">Padmanabhan P, McCullough A. Penile oxygen saturation in the fl accid and erect penis in men with and without erectile dysfunction. J Androl. 2007;28:223-8. doi:10.2164/jandrol.106.001313</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
