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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2017-5-2-60-68</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-151</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS ARTICLE</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЙ ВЗГЛЯД НА НОКТУРИЮ У ПАЦИЕНТОВ С ДОБРОКАЧЕСТВЕННОЙ ГИПЕРПЛАЗИЕЙ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>MODERN VIEW OF NOCTURIA IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2733-0619</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремов</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Еfremov</surname><given-names>М. Е.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-уролог ГБУЗ «Научно-исследовательский институт – Краевая клиническая больница №1 им. проф. С.В. Очаповского» МЗ Краснодарского края</p></bio><bio xml:lang="en"><p> </p><p> </p></bio><email xlink:type="simple">efremov.uro@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8335-2578</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведев</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Мedvedev</surname><given-names>В. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, профессор, заведующий кафедрой урологии ФГБОУ ВО «Кубанский государственный медицинский университет» МЗ РФ; заместитель главного врача по урологии, руководитель уронефрологического центра ГБУЗ «Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского» МЗ Краснодарского края</p><p> </p></bio><bio xml:lang="en"><p> </p><p> </p></bio><email xlink:type="simple">medvedev_vl@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2358-6302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шорников</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shornikov</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, ассистент кафедры урологии ФГБОУ ВО «Кубанский государственный медицинский университет» МЗ РФ, заведующий отделением функциональной диагностики №2 ГБУЗ «Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского» МЗ Краснодарского края</p></bio><email xlink:type="simple">shpvkr@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского» МЗ Краснодарского края</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institution - Regional Clinical Hospital №l of prof. S.V. Ochapovskogo</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «Научно-исследовательский институт – Краевая клиническая больница № 1 им. проф. С.В. Очаповского» МЗ Краснодарского края; ФГБОУ ВО «Кубанский государственный медицинский университет» МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institution - Regional Clinical Hospital №l of prof. S.V. Ochapovskogo; Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>09</day><month>07</month><year>2017</year></pub-date><volume>5</volume><issue>2</issue><fpage>60</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ефремов М.Е., Медведев В.Л., Шорников П.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Ефремов М.Е., Медведев В.Л., Шорников П.В.</copyright-holder><copyright-holder xml:lang="en">Еfremov М.Е., Мedvedev В.L., Shornikov P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/151">https://www.urovest.ru/jour/article/view/151</self-uri><abstract><p>Ноктурия традиционно считается преобладающим симптомом нижних мочевыводящих путей у пациентов с доброкачественной гиперплазией предстательной железы (ДГПЖ). Урологи и врачи общей практики становятся все более осведомленными и заинтересованы в определении вида ноктурии, о чем свидетельствуют крупные эпидемиологические исследования. Ноктурия является распространенным симптомом многих состояний и встречается у пациентов с разными заболеваниями. Этиология ноктурии является многофакторной. Современная классификация ноктурии базируется на данных дневников мочеиспускания и классифицируется следующим образом: суточная полиурия, ночная полиурия, сниженная ёмкость мочевого пузыря, расстройства сна и расстройства циркадного ритма. Суточная полиурия у взрослых определяется как объемом мочеобразования более 2,8 л в течение 24 ч. Значение объема мочеобразования 2,8 л в сутки применимо к человеку с массой тела 70 кг и скоростью диуреза более 40 мл/кг/24ч. Дневник мочеиспускания является важным инструментом оценки ноктурии, который может облегчить точную идентификацию потенциальных множественных причин у пациента, обеспечивая доказательства того, что этиология никтурии может быть отнесена к одной или комбинации причин: нарушений сна, ночной полиурии, суточная полиурия или уменьшенной емкости мочевого пузыря. Расстройства циркадных ритмов в патофизиологии ноктурии заслуживает дальнейшего внимания.</p></abstract><trans-abstract xml:lang="en"><p>Nocturia, awaking from sleep to void, has a negative impact on health and well-being. Nocturia traditionally has been regarded as a predominantly male condition, but it is just as prevalent in women as in men. Urologists and general practitioners are becoming increasingly aware of and interested in nocturia, as indicated by the recent increase in large epidemiologic studies and analyses and by initiatives such as the Nocturia Think Tank and The Consensus Statement from the Interdisciplinary Conference on Nocturia. Nocturia is a common symptom of many conditions and is encountered in patients presenting to services across different medical specialities and health disciplines. The causal pathway of nocturia is multi-factorial and differs between patients. There is currently no symptom-specific clinical algorithm for all-cause diagnosis of nocturia. A thorough history and assessment of number and times of voids, void volume, and fluid intake is essential for determining the etiology of a patient’s nocturia. With data obtained from the frequency-volume chart (FVC), which is used to collect quantitative voiding data, a patient’s nocturia may be classified as global polyuria, nocturnal polyuria, reduced bladder capacity, or a combination of these categories. Global polyuria is defined as 24-hr urinary output that exceeds 40 ml/kg body weight and results in increased 24-hr urinary frequency. Nocturia is a complex multifactorial condition that requires careful evaluation for appropriate diagnosis. The FVC is an essential evaluation tool that can facilitate accurate identification of the potential multiple causes of nocturia in an individual patient, providing evidence by which the etiology of nocturia can be categorized into one or a combination of categories of sleep disorders, nocturnal polyuria, global polyuria, and reduced bladder capacity. The role of the circadian clock in the pathophysiology of nocturia deserves further attention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ноктурия</kwd><kwd>суточная полиурия</kwd><kwd>ночная полиурия</kwd><kwd>сниженная ёмкость мочевого пузыря</kwd><kwd>расстройства сна</kwd><kwd>расстройства циркадного ритма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nocturia</kwd><kwd>global polyuria</kwd><kwd>nocturnal polyuria</kwd><kwd>reduced bladder capacity</kwd><kwd>sleep disorders</kwd><kwd>and circadian clock disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Power R, Fitzpatrick JM. Medical Treatment of BPH: An Update on Results. European Urology Supplements. 2004; 2(1):6-14. doi: 10.1016/j.euus.2004.01.003</mixed-citation><mixed-citation xml:lang="en">Power R, Fitzpatrick JM. Medical Treatment of BPH: An Update on Results. European Urology Supplements. 2004; 2(1):6-14. doi: 10.1016/j.euus.2004.01.003</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Mattsson S. Urinary incontinence and nocturia in healthy schoolchildren. Acta Paediatr. 1994;83:950–54. doi: 10.1111/j.1651-2227.1994.tb13179.x</mixed-citation><mixed-citation xml:lang="en">Mattsson S. Urinary incontinence and nocturia in healthy schoolchildren. Acta Paediatr. 1994;83:950–54. doi: 10.1111/j.1651-2227.1994.tb13179.x</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bosch JL, Weiss JP. The prevalence and causes of nocturia. J Urol 2010;184:440–6. doi: 10.1016/j. juro.2010.04.011</mixed-citation><mixed-citation xml:lang="en">Bosch JL, Weiss JP. The prevalence and causes of nocturia. J Urol 2010;184:440–6. doi: 10.1016/j. juro.2010.04.011</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Rosen RC, Holm-Larsen T, Kupelian V, Wein AJ. Consequences of nocturia. Postgrad Med. 2013;125(4):38-46. doi: 10.3810/pgm.2013.07.2673</mixed-citation><mixed-citation xml:lang="en">Rosen RC, Holm-Larsen T, Kupelian V, Wein AJ. Consequences of nocturia. Postgrad Med. 2013;125(4):38-46. doi: 10.3810/pgm.2013.07.2673</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Oelke M, Adler E, Marschall-Kehrel D, Herrmann TRW, Berges R. Nocturia: State of the art and critical analysis of current assessment and treatment strategies. World J Urol. 2014;32:1109–17. doi: 10.1007/s00345-014-1396- 0</mixed-citation><mixed-citation xml:lang="en">Oelke M, Adler E, Marschall-Kehrel D, Herrmann TRW, Berges R. Nocturia: State of the art and critical analysis of current assessment and treatment strategies. World J Urol. 2014;32:1109–17. doi: 10.1007/s00345-014-1396- 0</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Abrams P, Weiss J, Mattiasson A, Walter S, Weiss J. The efficacy and safety of oral desmopressin in the treatment of nocturia in men. Neurourol Urodyn. 2001;20:456–57.</mixed-citation><mixed-citation xml:lang="en">Abrams P, Weiss J, Mattiasson A, Walter S, Weiss J. The efficacy and safety of oral desmopressin in the treatment of nocturia in men. Neurourol Urodyn. 2001;20:456–57.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bing MH, Moller LA, Jennum P, Mortensen S, Lose G.. Nocturia and associated morbidity in a Danish population of men and women aged 60–80 years. BJU Int. 2008;102(7):808–14. doi: 10.1111/j.1464- 410X.2008.07813.x</mixed-citation><mixed-citation xml:lang="en">Bing MH, Moller LA, Jennum P, Mortensen S, Lose G.. Nocturia and associated morbidity in a Danish population of men and women aged 60–80 years. BJU Int. 2008;102(7):808–14. doi: 10.1111/j.1464- 410X.2008.07813.x</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Schatzl G, Temml C, Schmidbauer J, Dolezal B, Haidinger G, Madersbacher S. Cross-sectional study of nocturia in both sexes: analysis of a voluntary health screening project. Urology. 2000;56(1):71-75. doi: 10.1016/s0090- 4295(00)00603-8</mixed-citation><mixed-citation xml:lang="en">Schatzl G, Temml C, Schmidbauer J, Dolezal B, Haidinger G, Madersbacher S. Cross-sectional study of nocturia in both sexes: analysis of a voluntary health screening project. Urology. 2000;56(1):71-75. doi: 10.1016/s0090- 4295(00)00603-8</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart RB, Moore MT, May FE, Marks RG, Hale WE. Nocturia: a risk factor for falls in the elderly. J Am Geriatr Soc. 1992;40(12):1217–20. doi: 10.1111/j.1532- 5415.1992.tb03645.x</mixed-citation><mixed-citation xml:lang="en">Stewart RB, Moore MT, May FE, Marks RG, Hale WE. Nocturia: a risk factor for falls in the elderly. J Am Geriatr Soc. 1992;40(12):1217–20. doi: 10.1111/j.1532- 5415.1992.tb03645.x</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Brown JS, Vittinghoff E, Wyman JF, Stone KL, Nevitt MC et al. Urinary incontinence. Does it increase risk for falls and fractures. Study of Osteoporotic Fractures Research Group. J Am Geriatr Soc. 2000;48(7):721–25. doi: 10.1111/j.1532-5415.2000.tb04744.x</mixed-citation><mixed-citation xml:lang="en">Brown JS, Vittinghoff E, Wyman JF, Stone KL, Nevitt MC et al. Urinary incontinence. Does it increase risk for falls and fractures. Study of Osteoporotic Fractures Research Group. J Am Geriatr Soc. 2000;48(7):721–25. doi: 10.1111/j.1532-5415.2000.tb04744.x</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Greibling T. Overactive bladder in elderly men: Epidemiology, evaluation, clinical effects, and management. Curr Urol Rep. 2013;14:418–25. doi: 10.1007/s11934-013-0367-0</mixed-citation><mixed-citation xml:lang="en">Greibling T. Overactive bladder in elderly men: Epidemiology, evaluation, clinical effects, and management. Curr Urol Rep. 2013;14:418–25. doi: 10.1007/s11934-013-0367-0</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nakagawa H, Niu K, Hozawa A, Ikeda Y, Kaiho Y, et al. Impact of nocturia on bone fracture and mortality in older individuals: A Japanese longitudinal cohort study. J Urol. 2010;184(4):1413–8. doi: 10.1016/j.juro.2010.05.093</mixed-citation><mixed-citation xml:lang="en">Nakagawa H, Niu K, Hozawa A, Ikeda Y, Kaiho Y, et al. Impact of nocturia on bone fracture and mortality in older individuals: A Japanese longitudinal cohort study. J Urol. 2010;184(4):1413–8. doi: 10.1016/j.juro.2010.05.093</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gulur DM, Mevcha AM, Drake MJ. Nocturia as a manifestation of systemic disease. BJU Int. 2011;107(5):702-713. doi: 10.1111/j.1464- 410X.2010.09763.x</mixed-citation><mixed-citation xml:lang="en">Gulur DM, Mevcha AM, Drake MJ. Nocturia as a manifestation of systemic disease. BJU Int. 2011;107(5):702-713. doi: 10.1111/j.1464- 410X.2010.09763.x</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Drake MJ. Should nocturia not be called a lower urinary tract symptom? Eur Urol. 2015;67(2):289-90. doi: 10.1016/j.eururo.2014.09.024</mixed-citation><mixed-citation xml:lang="en">Drake MJ. Should nocturia not be called a lower urinary tract symptom? Eur Urol. 2015;67(2):289-90. doi: 10.1016/j.eururo.2014.09.024</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Endeshaw Y. Correlates of self-reported nocturia among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2009;64(1):142-8. doi: 10.1093/gerona/gln009</mixed-citation><mixed-citation xml:lang="en">Endeshaw Y. Correlates of self-reported nocturia among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2009;64(1):142-8. doi: 10.1093/gerona/gln009</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Greibling T. Overactive bladder in elderly men: Epidemiology, evaluation, clinical effects, and management. Curr Urol Rep. 2013;14(5):418-25. doi: 10.1007/s11934-013-0367-0</mixed-citation><mixed-citation xml:lang="en">Greibling T. Overactive bladder in elderly men: Epidemiology, evaluation, clinical effects, and management. Curr Urol Rep. 2013;14(5):418-25. doi: 10.1007/s11934-013-0367-0</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Van Dijk L, Kooy DG, Schellevis FG. Nocturia in the Dutch adult population. BJU Int. 2002;90(7):644-8</mixed-citation><mixed-citation xml:lang="en">Van Dijk L, Kooy DG, Schellevis FG. Nocturia in the Dutch adult population. BJU Int. 2002;90(7):644-8</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Asplund R. Mortality in the elderly in relation to nocturnal micturition. BJU Int. 1999;84(3):297-301. doi: 10.1046/j.1464-410x.1999.00157.x</mixed-citation><mixed-citation xml:lang="en">Asplund R. Mortality in the elderly in relation to nocturnal micturition. BJU Int. 1999;84(3):297-301. doi: 10.1046/j.1464-410x.1999.00157.x</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Chapple CR. Expert Opinion on Hours of Undisturbed Sleep (HUS): A new tool to evaluate the impact of nocturia on LUTS/BPH patients. Eur Urol. 2006; 1(5):1–2. doi: 10.1111/j.1464-410x.2006.06493.x</mixed-citation><mixed-citation xml:lang="en">Chapple CR. Expert Opinion on Hours of Undisturbed Sleep (HUS): A new tool to evaluate the impact of nocturia on LUTS/BPH patients. Eur Urol. 2006; 1(5):1–2. doi: 10.1111/j.1464-410x.2006.06493.x</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Asplund R, Aberg H. Nocturnal micturition, sleep and well-being in women of ages 40–64 years. Maturitas. 1996;24:73–81. doi: 10.1016/0378-5122(95)01021-1</mixed-citation><mixed-citation xml:lang="en">Asplund R, Aberg H. Nocturnal micturition, sleep and well-being in women of ages 40–64 years. Maturitas. 1996;24:73–81. doi: 10.1016/0378-5122(95)01021-1</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Nakagawa H, Ikeda Y, Kaiho Y, et al. Impact of nocturia on medical care use and its costs in an elderly population: 30 month prospective observation of national health insurance beneficiaries in Japan. Proc Int Cont Soc. 2009: 280.</mixed-citation><mixed-citation xml:lang="en">Nakagawa H, Ikeda Y, Kaiho Y, et al. Impact of nocturia on medical care use and its costs in an elderly population: 30 month prospective observation of national health insurance beneficiaries in Japan. Proc Int Cont Soc. 2009: 280.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Jennum P. Sleep and nocturia. BJU Int. 2002;90(3):21–24. doi: 10.1046/j.1464-410x.90.s3.6.x</mixed-citation><mixed-citation xml:lang="en">Jennum P. Sleep and nocturia. BJU Int. 2002;90(3):21–24. doi: 10.1046/j.1464-410x.90.s3.6.x</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Tinetti M, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988; 319(26):1701-7. doi: 10.1056/ nejm198812293192604</mixed-citation><mixed-citation xml:lang="en">Tinetti M, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988; 319(26):1701-7. doi: 10.1056/ nejm198812293192604</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Samaras N, Chevalley T, Samaras D, Gold G. Older patients in the emergency department: A review. Ann Emerg Med. 2010; 56(3):261-9. doi: 10.1016/j. annemergmed.2010.04.015</mixed-citation><mixed-citation xml:lang="en">Samaras N, Chevalley T, Samaras D, Gold G. Older patients in the emergency department: A review. Ann Emerg Med. 2010; 56(3):261-9. doi: 10.1016/j. annemergmed.2010.04.015</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Gillespie L, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH. Interventions for preventing falls in elderly people. Cochrane Database Syst Rev. 2009;2:CD000340. doi: 10.1002/14651858.cd000340. pub2</mixed-citation><mixed-citation xml:lang="en">Gillespie L, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH. Interventions for preventing falls in elderly people. Cochrane Database Syst Rev. 2009;2:CD000340. doi: 10.1002/14651858.cd000340. pub2</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Van Kerrebroeck P, Andersson KE. Terminology, Epidemiology, Etiology and Pathophysiology of nocturia. Neurourology and urodynamics. 2014;33(1):S2-5. doi: 10.1002/nau.22595</mixed-citation><mixed-citation xml:lang="en">Van Kerrebroeck P, Andersson KE. Terminology, Epidemiology, Etiology and Pathophysiology of nocturia. Neurourology and urodynamics. 2014;33(1):S2-5. doi: 10.1002/nau.22595</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Gulur DM, Mevcha AM, Drake WU. Nocturia as a manifestation of systemic disease. BJUJnt. 2011;107:702- 13. doi: 10.1111/j.1464-410x.2010.09763.x</mixed-citation><mixed-citation xml:lang="en">Gulur DM, Mevcha AM, Drake WU. Nocturia as a manifestation of systemic disease. BJUJnt. 2011;107:702- 13. doi: 10.1111/j.1464-410x.2010.09763.x</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Tikkinen KA, Johnson TM, Tammela TL, Sintonen H, Haukka J, et al. Nocturia frequency, bother, and quality of life: How often is too often? A population-based study in Finland. Eur Urol. 2010;57(3):488-96. doi: 10.1016/j. eururo.2009.03.080</mixed-citation><mixed-citation xml:lang="en">Tikkinen KA, Johnson TM, Tammela TL, Sintonen H, Haukka J, et al. Nocturia frequency, bother, and quality of life: How often is too often? A population-based study in Finland. Eur Urol. 2010;57(3):488-96. doi: 10.1016/j. eururo.2009.03.080</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Cornu J-N, Abrams P, Chapple CR, Dmochowski RR, Lemack GE, et al. A contemporary assessment of nocturia: Definition, epidemiology, pathophysiology, and management-a systematic review and metaanalysis. Eur Urol. 2012;62(5):877-90. doi: 10.1016/j. eururo.2012.07.004</mixed-citation><mixed-citation xml:lang="en">Cornu J-N, Abrams P, Chapple CR, Dmochowski RR, Lemack GE, et al. A contemporary assessment of nocturia: Definition, epidemiology, pathophysiology, and management-a systematic review and metaanalysis. Eur Urol. 2012;62(5):877-90. doi: 10.1016/j. eururo.2012.07.004</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Weiss JP, Blaivas JG. Nocturnal polyuria versus overactive bladder in nocturia. Urology. 2002;60:28–32. doi: 10.1016/s0090-4295(02)01789-2</mixed-citation><mixed-citation xml:lang="en">Weiss JP, Blaivas JG. Nocturnal polyuria versus overactive bladder in nocturia. Urology. 2002;60:28–32. doi: 10.1016/s0090-4295(02)01789-2</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Umlauf MG, Chasens ER. Sleep disordered breathing and nocturnal polyuria: Nocturia and enuresis. Sleep Med Rev. 2003;7:403-11. doi: 10.1053/smrv.2002.0273</mixed-citation><mixed-citation xml:lang="en">Umlauf MG, Chasens ER. Sleep disordered breathing and nocturnal polyuria: Nocturia and enuresis. Sleep Med Rev. 2003;7:403-11. doi: 10.1053/smrv.2002.0273</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Asplund R, Aberg H. Diurnal variation in the levels of antidiuretic hormone in the elderly. J Intern Med. 1991;229:131-4. doi: 10.1111/j.1365-2796.1991. tb00320.x</mixed-citation><mixed-citation xml:lang="en">Asplund R, Aberg H. Diurnal variation in the levels of antidiuretic hormone in the elderly. J Intern Med. 1991;229:131-4. doi: 10.1111/j.1365-2796.1991. tb00320.x</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Parthasarathy S, Fitzgerald M, Goodwin JL, Unruh M, Guerra S, Quan SF. Nocturia, sleep-disordered breathing, and cardiovascular morbidity in a community-based cohort. PLoS ONE. 2012;7(2):e30969. doi: 10.1371/ journal.pone.0030969</mixed-citation><mixed-citation xml:lang="en">Parthasarathy S, Fitzgerald M, Goodwin JL, Unruh M, Guerra S, Quan SF. Nocturia, sleep-disordered breathing, and cardiovascular morbidity in a community-based cohort. PLoS ONE. 2012;7(2):e30969. doi: 10.1371/ journal.pone.0030969</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Weiss JP, Bosch JL, Drake M, Dmochowski RR, Hashim H et al. Nocturia think tank: Focus on nocturnal polyuria: ICI-RS 2011. Neurourol Urodyn. 2012;31(3):330-9. doi: 10.1002/nau.22219</mixed-citation><mixed-citation xml:lang="en">Weiss JP, Bosch JL, Drake M, Dmochowski RR, Hashim H et al. Nocturia think tank: Focus on nocturnal polyuria: ICI-RS 2011. Neurourol Urodyn. 2012;31(3):330-9. doi: 10.1002/nau.22219</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">van Doorn B, Blanker MH, Kok ET, Westers P, Bosch JL. Prevalence, incidence and resolution of nocturnal polyuria in a longitudinal community-based study of older men: The Krimpen study. Eur Urol. 2013;63(3):542- 7. doi: 10.1016/j.eururo.2012.10.004</mixed-citation><mixed-citation xml:lang="en">van Doorn B, Blanker MH, Kok ET, Westers P, Bosch JL. Prevalence, incidence and resolution of nocturnal polyuria in a longitudinal community-based study of older men: The Krimpen study. Eur Urol. 2013;63(3):542- 7. doi: 10.1016/j.eururo.2012.10.004</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Bosch JL, Everaert K, Weiss JP, Hashim H, Rahnama’i MS, et al. Would a New Definition and Classification of Nocturia and Nocturnal Polyuria Improve Our Management of Patients? ICI-RS 2014. Neurourol Urodyn. 2016;35(2):283-7. doi: 10.1002/nau.22772</mixed-citation><mixed-citation xml:lang="en">Bosch JL, Everaert K, Weiss JP, Hashim H, Rahnama’i MS, et al. Would a New Definition and Classification of Nocturia and Nocturnal Polyuria Improve Our Management of Patients? ICI-RS 2014. Neurourol Urodyn. 2016;35(2):283-7. doi: 10.1002/nau.22772</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Miyazato M, Tana T, Higa A, Oshiro T, Namitome R, et al. Prevalence and risk factors for nocturia in an outpatient clinic. Luts. 2014;6(3):167–71. doi: 10.1111/ luts.12039</mixed-citation><mixed-citation xml:lang="en">Miyazato M, Tana T, Higa A, Oshiro T, Namitome R, et al. Prevalence and risk factors for nocturia in an outpatient clinic. Luts. 2014;6(3):167–71. doi: 10.1111/ luts.12039</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Umlauf M, Kurtzer E, Valappil T, Burgio K, Pillion D, Goode P. Sleep-disordered breathing as a mechanism for nocturia: Preliminary findings. Ostomy Wound Manage. 1999;45(12):52–60.</mixed-citation><mixed-citation xml:lang="en">Umlauf M, Kurtzer E, Valappil T, Burgio K, Pillion D, Goode P. Sleep-disordered breathing as a mechanism for nocturia: Preliminary findings. Ostomy Wound Manage. 1999;45(12):52–60.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Umlauf MG, Chasens ER, Greevy RA, Arnold J, Burgio KL, Pillion DJ. Obstructive sleep apnea, nocturia and polyuria in older adults. Sleep. 2004;27(1):139–44.</mixed-citation><mixed-citation xml:lang="en">Umlauf MG, Chasens ER, Greevy RA, Arnold J, Burgio KL, Pillion DJ. Obstructive sleep apnea, nocturia and polyuria in older adults. Sleep. 2004;27(1):139–44.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Chasens ER, Umlauf MG. Nocturia: A problem that disrupts sleep and predicts obstructive sleep apnea. Geriatric nursing. 2003;24(2):76-81. doi: 10.1067/mgn.2003.27</mixed-citation><mixed-citation xml:lang="en">Chasens ER, Umlauf MG. Nocturia: A problem that disrupts sleep and predicts obstructive sleep apnea. Geriatric nursing. 2003;24(2):76-81. doi: 10.1067/mgn.2003.27</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Miyauchi Y, Okazoe H, Okujyo M, Inada F, Kakehi T, et al. Effect of the continuous positive airway pressure on the nocturnal urine volume or night-time frequency in patients with obstructive sleep apnea syndrome. Urology. 2015;85(2):333-6. doi: 10.1016/j.urology.2014.11.002</mixed-citation><mixed-citation xml:lang="en">Miyauchi Y, Okazoe H, Okujyo M, Inada F, Kakehi T, et al. Effect of the continuous positive airway pressure on the nocturnal urine volume or night-time frequency in patients with obstructive sleep apnea syndrome. Urology. 2015;85(2):333-6. doi: 10.1016/j.urology.2014.11.002</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">van Kerrebroeck P, Abrams P, Chaikin D, Donovan J, Fonda D, et al. The standardisation of terminology in nocturia: Report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn. 2002;21(2):179-83. doi: 10.1002/nau.10053</mixed-citation><mixed-citation xml:lang="en">van Kerrebroeck P, Abrams P, Chaikin D, Donovan J, Fonda D, et al. The standardisation of terminology in nocturia: Report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn. 2002;21(2):179-83. doi: 10.1002/nau.10053</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Chappie CR, Cornu IN, Abrams P, Dmochowski RR, Lemack GE et al. A contemporary assessment of nocturia: Definition, epidemiology, pathophysiology, and management. Eur Urol. 2012;62(5):877-90. doi: 10.1016/j.eururo.2012.07.004</mixed-citation><mixed-citation xml:lang="en">Chappie CR, Cornu IN, Abrams P, Dmochowski RR, Lemack GE et al. A contemporary assessment of nocturia: Definition, epidemiology, pathophysiology, and management. Eur Urol. 2012;62(5):877-90. doi: 10.1016/j.eururo.2012.07.004</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Weiss JP, Blaivas JG, Bliwise DL, Dmochowski RR, Dubeau CE et al. The evaluation and treatment of nocturia: A consensus statement. BJU Int. 2011;108(1):6-21. doi: 10.1111/j.1464-410x.2011.10175.x</mixed-citation><mixed-citation xml:lang="en">Weiss JP, Blaivas JG, Bliwise DL, Dmochowski RR, Dubeau CE et al. The evaluation and treatment of nocturia: A consensus statement. BJU Int. 2011;108(1):6-21. doi: 10.1111/j.1464-410x.2011.10175.x</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Pesonen JS, Cartwright R, Santti H, et al. The impact of nocturia on mortality: A systematic review and metaanalysis. Neurourol Urodyn. 2014;33:783–84.</mixed-citation><mixed-citation xml:lang="en">Pesonen JS, Cartwright R, Santti H, et al. The impact of nocturia on mortality: A systematic review and metaanalysis. Neurourol Urodyn. 2014;33:783–84.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Weiss JP, Blaivas JG, Blanker MH, Bliwise DL, Dmochowski RR, et al. The New England Research Institutes, Inc. (NERI) Nocturia Advisory Conference 2012: Focus on outcomes of therapy. BJU Int. 2013;111(5):700-716. doi: 10.1111/j.1464-410x.2012.11749.x</mixed-citation><mixed-citation xml:lang="en">Weiss JP, Blaivas JG, Blanker MH, Bliwise DL, Dmochowski RR, et al. The New England Research Institutes, Inc. (NERI) Nocturia Advisory Conference 2012: Focus on outcomes of therapy. BJU Int. 2013;111(5):700-716. doi: 10.1111/j.1464-410x.2012.11749.x</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Bosch JL, Weiss JP. The prevalence and causes of nocturia. J Urol. 2010;184:440-5. doi: 10.1016/j.juro.2010.04.011</mixed-citation><mixed-citation xml:lang="en">Bosch JL, Weiss JP. The prevalence and causes of nocturia. J Urol. 2010;184:440-5. doi: 10.1016/j.juro.2010.04.011</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Dibner C, Schibler U, Albrecht U. The mammalian circadianti ming system: Organization and coordination of central and peripheral clocks. Annu Rev Physiol. 2010;72:517- 49. doi: 10.1146/annurev-physiol-021909-135821</mixed-citation><mixed-citation xml:lang="en">Dibner C, Schibler U, Albrecht U. The mammalian circadianti ming system: Organization and coordination of central and peripheral clocks. Annu Rev Physiol. 2010;72:517- 49. doi: 10.1146/annurev-physiol-021909-135821</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Reppert SM, Weaver DR. Coordination of circadianti ming in mammals. Nature. 2002;418:935-41. doi: 10.1038/ nature00965</mixed-citation><mixed-citation xml:lang="en">Reppert SM, Weaver DR. Coordination of circadianti ming in mammals. Nature. 2002;418:935-41. doi: 10.1038/ nature00965</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Negoro H, Kanematsu A, Doi M, Suadicani SO, Matsuo M et al. Involvement of urinary bladder Connexin43 and the circadian clock in coordination of diurnal micturition rhythm. Nat Commun. 2012;3:809. doi: 10.1038/ncomms1812</mixed-citation><mixed-citation xml:lang="en">Negoro H, Kanematsu A, Doi M, Suadicani SO, Matsuo M et al. Involvement of urinary bladder Connexin43 and the circadian clock in coordination of diurnal micturition rhythm. Nat Commun. 2012;3:809. doi: 10.1038/ncomms1812</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Abrams P. Nocturia: the major problem in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction (LUTS/BPO). Eur Urol. 2005;6(3):8–16. doi: 10.1016/s1569-9056(05)80002-8</mixed-citation><mixed-citation xml:lang="en">Abrams P. Nocturia: the major problem in patients with lower urinary tract symptoms suggestive of benign prostaƟ c obstrucƟ on (LUTS/BPO). Eur Urol. 2005;6(3):8–16. doi: 10.1016/s1569-9056(05)80002-8</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Chang SC, Lin AT, Chen KK, Chang LS. MulƟ factorial nature of male nocturia. Urology. 2006;67(3):541-4. doi: 10.1016/j. urology.2005.09.037</mixed-citation><mixed-citation xml:lang="en">Chang SC, Lin AT, Chen KK, Chang LS. Multifactorial nature of male nocturia. Urology. 2006;67(3):541-4. doi: 10.1016/j. urology.2005.09.037</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
