<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2026-14-4-58-67</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-1259</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Хирургическое лечение преждевременной эякуляции и его влияние на репродуктивную функцию</article-title><trans-title-group xml:lang="en"><trans-title>Premature ejaculation: surgical treatment and its impact on reproductive function</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-1922-8590</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаипов</surname><given-names>М. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Shaipov</surname><given-names>M. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марат Хусаинович Шаипов  </p><p>Москва</p></bio><bio xml:lang="en"><p>Marat Kh. Shaipov </p><p>Moscow </p></bio><email xlink:type="simple">shaipovmh@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3902-9236</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шатылко</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shatylko</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарас Валерьевич Шатылко — канд. мед. наук </p><p>Москва</p></bio><bio xml:lang="en"><p>Taras V. Shatylko — Cand.Sc.(Med) </p><p>Moscow </p></bio><email xlink:type="simple">dialectic.law@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9128-2714</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гамидов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gamidov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сафар Исраилович Гамидов — д-р мед. наук, профессор </p><p>Москва</p></bio><bio xml:lang="en"><p>Safar I. Gamidov— Dr.Sc.(Med), Full Prof. </p><p>Moscow </p></bio><email xlink:type="simple">safargamidov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6948-6075</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калинкин</surname><given-names>Д. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalinkin</surname><given-names>D. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Евгеньевич Калинкин — д-р мед. наук; доцент </p><p>Томск </p></bio><bio xml:lang="en"><p>Dmitrii E. Kalinkin — Dr.Sc.(Med); Assoc.Prof. (Docent)</p><p>Tomsk</p></bio><email xlink:type="simple">kalinkin750@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-7797-8369</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белобородова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Beloborodova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алёна Валерьевна Белобородова  </p><p> Санкт-Петербург </p></bio><bio xml:lang="en"><p>Alyena V. Beloborodova </p><p>Saint Petersburg</p></bio><email xlink:type="simple">dr.alena.beloborodova@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-6144-0141</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gulin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иван Владимирович Гулин </p><p>Дзержинск </p></bio><bio xml:lang="en"><p>Ivan V. Gulin </p><p>Dzerzhinsk</p></bio><email xlink:type="simple">urolog.gulin@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-7957-3017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Закаряев</surname><given-names>Э. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakaryaev</surname><given-names>E. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Эльдар Танзилович Закаряев </p><p>Москва</p></bio><bio xml:lang="en"><p>Eldar T. Zakaryaev</p><p>Moscow</p></bio><email xlink:type="simple">23zakaryaev@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова ; Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology ; Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Сеть многопрофильных клиник доказательной медицины Фомина</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Multidisciplinary Clinics of Evidence-Based Medicine «Fomin Clinic»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Больница скорой медицинской помощи г. Дзержинска</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Dzerzhinsk Emergency Medical Care Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>22</day><month>08</month><year>2026</year></pub-date><volume>14</volume><issue>4</issue><fpage>58</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шаипов М.Х., Шатылко Т.В., Гамидов С.И., Калинкин Д.Е., Белобородова А.В., Гулин И.В., Закаряев Э.Т., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Шаипов М.Х., Шатылко Т.В., Гамидов С.И., Калинкин Д.Е., Белобородова А.В., Гулин И.В., Закаряев Э.Т.</copyright-holder><copyright-holder xml:lang="en">Shaipov M.K., Shatylko T.V., Gamidov S.I., Kalinkin D.E., Beloborodova A.V., Gulin I.V., Zakaryaev E.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/1259">https://www.urovest.ru/jour/article/view/1259</self-uri><abstract><p>Введение. Сексуальные дисфункции (эректильная дисфункция, нарушения эякуляции) широко распространены среди мужчин, негативно влияют на их репродуктивную функцию, в силу чего требуют своевременного выявления и эффективного лечения.Цель исследования. Оценить эффективность хирургических методов лечения преждевременной эякуляции и их влияние на репродуктивную функцию.Материалы и методы. В исследование были включены 116 мужчин с преждевременной эякуляцией и активным желанием сохранить и реализовать репродуктивную функцию. Диагноз «Преждевременная эякуляция» опирался на критерии Международного общества сексуальной медицины. Мужчины были обследованы для установления формы преждевременной эякуляции и ведущего этиологического фактора (осмотр наружных половых органов, пальцевое ректальное исследование, лидокаиновый тест, гормональное обследование (уровни тестостерона, эстрадиола, ЛГ, ФСГ, пролактина, ТТГ, Т3, Т4 в сыворотке крови), бактериологическое исследование и ПЦР в реальном времени эякулята и секрета предстательной железы, а также микроскопия последнего; ультразвуковое исследование органов мошонки, трансректальное ультразвуковое исследование простаты и семенных пузырьков. Оперативное лечение в объёме селективной микрохирургической денервации головки полового члена было выполнено 41 пациенту.Результаты. У 34 (82,9%) пациентов через 3 месяца после денервации средняя продолжительность вагинального полового акта составила более 2 минут. Таким образом, у большинства пациентов хирургическое вмешательство позволило добиться спонтанной регулярной половой жизни с удовлетворительной продолжительностью полового акта. Значимых различий между дооперационными и послеоперационными показателями спермограммы выявлено не было.Заключение. Селективная микрохирургическая денервация головки пениса позволяет пациентам с первичной преждевременной эякуляцией нормализовать регулярную сексуальную активность, исключив методы лечения, не позволяющие (или снижающие вероятность) зачатия естественным путём.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. Sexual dysfunctions, including erectile dysfunction and ejaculatory disorders, are highly prevalent among men and can adversely affect reproductive potential, making timely diagnosis and effective treatment essential.Objective. To evaluate the efficacy of surgical treatment for premature ejaculation and its impact on reproductive function.Materials &amp; methods. The study included 116 men with premature ejaculation who expressed a strong desire to preserve and realise their reproductive potential. The diagnosis was based on the International Society for Sexual Medicine criteria. Patients underwent a comprehensive evaluation to determine the form of premature ejaculation and the main aetiological factor, including examination of the external genitalia, digital rectal examination, lidocaine test, hormonal assessment (serum testosterone, estradiol, luteinising hormone, follicle-stimulating hormone, prolactin, thyroid-stimulating hormone, triiodothyronine, and thyroxine), bacteriological testing and real-time PCR of the ejaculate and prostatic secretion, microscopy of prostatic secretion, as well as ultrasound of the scrotal organs and transrectal ultrasound of the prostate and seminal vesicles. Selective microsurgical denervation of the penile glans was performed in 41 patients.Results. Three months after denervation, 34 patients (82.9%) achieved an average vaginal intercourse duration of more than 2 minutes. Thus, in most patients, surgery made it possible to establish spontaneous regular sexual activity with a satisfactory duration of intercourse. No significant differences were found between preoperative and postoperative semen parameters.Conclusion. Selective microsurgical denervation of the penile glans enables patients with primary premature ejaculation to achieve regular sexual activity while avoiding treatment methods that prevent or reduce the likelihood of natural conception.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>репродуктивная функция</kwd><kwd>сексуальная дисфункция</kwd><kwd>преждевременная эякуляция</kwd><kwd>хирургическое лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>reproductive function</kwd><kwd>sexual dysfunction</kwd><kwd>premature ejaculation</kwd><kwd>surgical treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Thoma M.E., McLain A.C., Louis J.F., King R.B., Trumble A.C., Sundaram R, Buck Louis G.M. Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach. Fertil Steril. 2013;99(5):1324-1331.e1. DOI: 10.1016/j.fertnstert.2012.11.037</mixed-citation><mixed-citation xml:lang="en">Thoma M.E., McLain A.C., Louis J.F., King R.B., Trumble A.C., Sundaram R, Buck Louis G.M. Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach. Fertil Steril. 2013;99(5):1324-1331.e1. DOI: 10.1016/j.fertnstert.2012.11.037</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple. 2000. Accessed on June 7, 2025. URL: https://www.who.int/publications/i/item/9780521774741</mixed-citation><mixed-citation xml:lang="en">WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple. 2000. Accessed on June 7, 2025. URL: https://www.who.int/publications/i/item/9780521774741</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Шатылко Т.В., Маммаев Р.У., Гамидов С.И., Макарова Н.П., Лобанова Н.Н., Попова А.Ю., Кулакова Е.В., Гамидова П.С. Динамика показателей эякулята за период с 2017 по 2023 год: ретроспективный одноцентровой анализ. Андрология и генитальная хирургия. 2024;25(2):54-59. DOI: 10.62968/2070-9781-2024-25-2-54-59</mixed-citation><mixed-citation xml:lang="en">Shatylko T.V., Mammaev R.U., Gamidov S.I., Makarova N.P., Lobanova N.N., Popova A.Y., Kulakova E.V., Gamidova P.S. Dynamics of ejaculate parameters from 2017 to 2023: a retrospective single-center analysis. Andrology and Genital Surgery. 2024;25(2):54-60. (In Russian). DOI: 10.62968/2070-9781-2024-25-2-54-59</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Lewis R.W., Fugl-Meyer K.S., Corona G, Hayes R.D., Laumann E.O., Moreira E.D. Jr, Rellini A.H., Segraves T. Definitions/epidemiology/risk factors for sexual dysfunction. J Sex Med. 2010;7(4 Pt 2):1598-1607. DOI: 10.1111/j.1743-6109.2010.01778.x</mixed-citation><mixed-citation xml:lang="en">Lewis R.W., Fugl-Meyer K.S., Corona G, Hayes R.D., Laumann E.O., Moreira E.D. Jr, Rellini A.H., Segraves T. Definitions/epidemiology/risk factors for sexual dysfunction. J Sex Med. 2010;7(4 Pt 2):1598-1607. DOI: 10.1111/j.1743-6109.2010.01778.x</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lara L.A., Salomao P.B., Romao A.P., Reis R.M., Navarro P.A., Rosa-eSilva A.C., Ferriani R.A. Effect of infertility on the sexual function of couples: state of the art. Recent Pat Endocr Metab Immune Drug Discov. 2015;9(1):46-53. DOI: 10.2174/1872214809666150416151811</mixed-citation><mixed-citation xml:lang="en">Lara L.A., Salomao P.B., Romao A.P., Reis R.M., Navarro P.A., Rosa-eSilva A.C., Ferriani R.A. Effect of infertility on the sexual function of couples: state of the art. Recent Pat Endocr Metab Immune Drug Discov. 2015;9(1):46-53. DOI: 10.2174/1872214809666150416151811</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Ferraresi S.R., Lara L.A., de Sá M.F., Reis R.M., Rosa e Silva A.C. Current research on how infertility affects the sexuality of men and women. Recent Pat Endocr Metab Immune Drug Discov. 2013;7(3):198-202. DOI: 10.2174/18722148113079990009</mixed-citation><mixed-citation xml:lang="en">Ferraresi S.R., Lara L.A., de Sá M.F., Reis R.M., Rosa e Silva A.C. Current research on how infertility affects the sexuality of men and women. Recent Pat Endocr Metab Immune Drug Discov. 2013;7(3):198-202. DOI: 10.2174/18722148113079990009</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Lotti F., Maggi M. Sexual dysfunction and male infertility. Nat Rev Urol. 2018;15(5):287-307. DOI: 10.1038/nrurol.2018.20</mixed-citation><mixed-citation xml:lang="en">Lotti F., Maggi M. Sexual dysfunction and male infertility. Nat Rev Urol. 2018;15(5):287-307. DOI: 10.1038/nrurol.2018.20</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Gao J., Zhang X., Su P., Liu J., Shi K., Hao Z., Zhou J., Liang C. Relationship between sexual dysfunction and psychological burden in men with infertility: a large observational study in China. J Sex Med. 2013;10(8):1935-1942. DOI: 10.1111/jsm.12207</mixed-citation><mixed-citation xml:lang="en">Gao J., Zhang X., Su P., Liu J., Shi K., Hao Z., Zhou J., Liang C. Relationship between sexual dysfunction and psychological burden in men with infertility: a large observational study in China. J Sex Med. 2013;10(8):1935-1942. DOI: 10.1111/jsm.12207</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Yu X., Zhang S., Wei Z., Zhang X., Wang Q. Prevalence of sexual dysfunction among the male populations who seeking medical care for infertility, pregnancy loss and preconception care: a cross-sectional study. Sci Rep. 2022;12(1):12969. DOI: 10.1038/s41598-022-17201-3</mixed-citation><mixed-citation xml:lang="en">Yu X., Zhang S., Wei Z., Zhang X., Wang Q. Prevalence of sexual dysfunction among the male populations who seeking medical care for infertility, pregnancy loss and preconception care: a cross-sectional study. Sci Rep. 2022;12(1):12969. DOI: 10.1038/s41598-022-17201-3</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hassanzadeh K., Yavari-kia P., Ahmadi-Asrbadr Y., Nematzadeh-Pakdel A., Alikhah H. Features of premature ejaculation in infertile men. Pak J Biol Sci. 2010;13(18):911-915. DOI: 10.3923/pjbs.2010.911.915</mixed-citation><mixed-citation xml:lang="en">Hassanzadeh K., Yavari-kia P., Ahmadi-Asrbadr Y., Nematzadeh-Pakdel A., Alikhah H. Features of premature ejaculation in infertile men. Pak J Biol Sci. 2010;13(18):911-915. DOI: 10.3923/pjbs.2010.911.915</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Omu F.E., Omu A.E. Emotional reaction to diagnosis of infertility in Kuwait and successful clients’ perception of nurses’ role during treatment. BMC Nurs. 2010;9:5. DOI: 10.1186/1472-6955-9-5</mixed-citation><mixed-citation xml:lang="en">Omu F.E., Omu A.E. Emotional reaction to diagnosis of infertility in Kuwait and successful clients’ perception of nurses’ role during treatment. BMC Nurs. 2010;9:5. DOI: 10.1186/1472-6955-9-5</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Shindel A.W., Nelson C.J., Naughton C.K., Mulhall J.P. Premature ejaculation in infertile couples: prevalence and correlates. J Sex Med. 2008;5(2):485-491. DOI: 10.1111/j.1743-6109.2007.00690.x</mixed-citation><mixed-citation xml:lang="en">Shindel A.W., Nelson C.J., Naughton C.K., Mulhall J.P. Premature ejaculation in infertile couples: prevalence and correlates. J Sex Med. 2008;5(2):485-491. DOI: 10.1111/j.1743-6109.2007.00690.x</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Lotti F., Corona G., Rastrelli G., Forti G., Jannini E.A., Maggi M. Clinical correlates of erectile dysfunction and premature ejaculation in men with couple infertility. J Sex Med. 2012;9(10):2698-2707. DOI: 10.1111/j.1743-6109.2012.02872.x</mixed-citation><mixed-citation xml:lang="en">Lotti F., Corona G., Rastrelli G., Forti G., Jannini E.A., Maggi M. Clinical correlates of erectile dysfunction and premature ejaculation in men with couple infertility. J Sex Med. 2012;9(10):2698-2707. DOI: 10.1111/j.1743-6109.2012.02872.x</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Lotti F., Corona G., Castellini G., Maseroli E., Fino M.G., Cozzolino M, Maggi M. Semen quality impairment is associated with sexual dysfunction according to its severity. Hum Reprod. 2016;31(12):2668-2680. DOI: 10.1093/humrep/dew246</mixed-citation><mixed-citation xml:lang="en">Lotti F., Corona G., Castellini G., Maseroli E., Fino M.G., Cozzolino M, Maggi M. Semen quality impairment is associated with sexual dysfunction according to its severity. Hum Reprod. 2016;31(12):2668-2680. DOI: 10.1093/humrep/dew246</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Гамидов С.B., Попова А.Ю., Шатылко Т.В., Ли К.И., Сафиуллин Р.И. Оценка эффективности Дапоксетина при первичной и вторичной формах преждевременной эякуляции. Урология. 2022;(1):46-49. DOI: 10.18565/urology.2022.1.46-49</mixed-citation><mixed-citation xml:lang="en">Gamidov S.I., Popova A.Yu., Shatylko T.V., Li K.I., Safiullin R.I. Evaluation of the efficacy of dapoxetine in primary and secondary forms of premature ejaculation. Urologiia. 2022;(1):46-49. (In Russian). DOI: 10.18565/urology.2022.1.46-49</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Аляев Ю.Г., Ахвледиани Н.Д. Сравнение эффективности селективной пенильной денервации и циркумцизио при первичной преждевременной эякуляции. Урология. 2016;(1-S1):60-64. eLIBRARY ID: 25849402; EDN: VTRFPR</mixed-citation><mixed-citation xml:lang="en">Alyaev Ju.G., Ahvlediani N.D. Comparing efficacy of selective penile denervation and circumcision for primary premature ejaculation. Urologiia. 2016;(1-S1):60-64. (In Russian). eLIBRARY ID: 25849402; EDN: VTRFPR</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Камалов А.А., Охоботов Д.А., Фролова М.В., Тивтикян А.С., Нестерова О.Ю. Преждевременная эякуляция: основные физиологические механизмы и новые подходы к лечению. Урология. 2020;(1):95-102. DOI: 10.18565/urology.2020.6.95-102</mixed-citation><mixed-citation xml:lang="en">Kamalov A.A., Ohobotov D.A., Frolova M.V., Tivtikyan A.S., Nesterova O.Y. Premature ejaculation: the main physiological mechanisms and new approaches to the treatment. Urologiia. 2020;(1):95-102. (In Russian). DOI: 10.18565/urology.2020.6.95-102</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
