urovestВестник урологииUrology Herald2308-6424Rostov State Medical University10.21886/2308-6424-2025-13-4-89-96urovest-1111Research ArticleОБЗОРЫ ПУБЛИКАЦИЙ – ТЕКУЩЕЕ МНЕНИЕCURRENT STATE-OF-THE-ARTПатоспермия и актуальные методы её леченияSemen parameter disorders and methods of correctionhttps://orcid.org/0000-0002-5741-6408НеймаркА. И.NeymarkA. I.

Александр Израилевич Неймарк – д-р мед. наук; профессор

Барнаул

Alexander I. Neymark – Dr.Sc.(Med), Full Prof.

Barnaul

urologagmu@mail.ruhttps://orcid.org/0009-0004-4489-2431ЯковлевА. В.YakovlevA. V.

Андрей Владимирович Яковлев – канд. мед. наук

Барнаул

Andrey V. Yakovlev – Cand.Sc.(Med)

Barnaul

andryakovlev81@mail.ruhttps://orcid.org/0000-0002-3450-3875КабловаИ. В.KablovaI. V.

Ирина Викторовна Каблова – канд. мед. наук

Барнаул

Irina V. Kablova – Cand.Sc.(Med)

Barnaul

irina_kablova@mail.ruhttps://orcid.org/0000-0002-3003-4362МанасоваЗ. Ш.ManasovaZ. Sh.

Зарипат Шахбановна Манасова – канд. мед. наук

Москва

Zaripat Sh. Manasova – Cand.Sc.(Med)

Moscow

zmanasova@yandex.ruhttps://orcid.org/0000-0001-5425-7707АндриуцаН. С.AndriutsaN. S.

Наталья Сергеевна Андриуца – канд. мед. наук

Москва

Natalia S. Andriutsa – Cand.Sc.(Med)

Moscow

andriutsa_n_s@staff.sechenov.ruhttps://orcid.org/0000-0001-5758-8552ЕршовА. В.YershovA. V.

Антон Валерьевич Ершов – д-р мед. наук

Москва

Anton V. Yershov – Dr.Sc.(Med)

Moscow

salavatprof@mail.ruАлтайский государственный медицинский университетРоссияAltai State Medical UniversityRussian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова Минздрава РоссииРоссияSechenov First Moscow State Medical University (Sechenov University)Russian FederationПервый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России; Научно-исследовательский институт общей реаниматологии им. В.А. НеговскогоРоссияSechenov First Moscow State Medical University (Sechenov University); Negovsky Research Institute of General Emergency CareRussian Federation2025151120251348996Copyright © Неймарк А.И., Яковлев А.В., Каблова И.В., Манасова З.Ш., Андриуца Н.С., Ершов А.В., 20252025Неймарк А.И., Яковлев А.В., Каблова И.В., Манасова З.Ш., Андриуца Н.С., Ершов А.В.Neymark A.I., Yakovlev A.V., Kablova I.V., Manasova Z.S., Andriutsa N.S., Yershov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.urovest.ru/jour/article/view/1111

Обзор литературы посвящён актуальной медико-социальной проблеме – мужскому бесплодию. В статье приведены данные о факторах, способствующих нарушению сперматогенеза и развитию патоспермии. Показана роль окислительного стресса в патогенезе патоспермии и мужского бесплодия. Представлены методы лечения патоспермии. Подчёркнута роль антиоксидантной терапии в лечении патоспермии. Приведены данные о высокой эффективности мелатонина и положительном его влиянии на показатели спермограммы.

The article presents data on factors contributing to impaired spermatogenesis and the development of semen disorders (SD). The role of oxidative stress in the pathogenesis of SD and male infertility is demonstrated. Various therapeutic approaches to SD are outlined, with particular emphasis on the role of antioxidant therapy in its management. Evidence is provided highlighting the high efficacy of melatonin and its beneficial impact on semen parameters.

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The authors declare that there are no conflicts of interest present.