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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">urovest</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник урологии</journal-title><trans-title-group xml:lang="en"><trans-title>Urology Herald</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2308-6424</issn><publisher><publisher-name>Rostov State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21886/2308-6424-2025-13-1-48-55</article-id><article-id custom-type="elpub" pub-id-type="custom">urovest-1010</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Аффективные расстройства у больных до и после лазерной энуклеации предстательной железы</article-title><trans-title-group xml:lang="en"><trans-title>Affective disorders before and after laser enucleation of the prostate</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6661-8570</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенов</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenov</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семенов Антон Павлович</p><p>Москва</p></bio><bio xml:lang="en"><p>Semenov Anton Pavlovich</p></bio><email xlink:type="simple">semenovap.uro@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8202-3844</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсуфов</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusufov</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анвар Гаджиевич Юсуфов — канд. мед. наук </p><p>Москва</p></bio><bio xml:lang="en"><p>Anvar G. Yusufov — Cand.Sc.(Med)</p></bio><email xlink:type="simple">anvar.yusufov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2944-2668</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуспанов</surname><given-names>Р. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Guspanov</surname><given-names>R. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ренат Иватуллаевич Гуспанов — канд. мед. наук</p><p>Москва</p></bio><bio xml:lang="en"><p> Renat I. Guspanov — Cand.Sc.(Med)</p></bio><email xlink:type="simple">uroguspanov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3764-6131</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Владиславович Котов — д-р мед. наук, профессор</p><p>Москва</p></bio><bio xml:lang="en"><p>Sergey V. Kotov — Dr.Sc.(Med), Full Prof.</p></bio><email xlink:type="simple">urokotov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н. И. Пирогова; Московский многопрофильный клинический центр «Коммунарка»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University) ; "Kommunarka" Moscow Multidisciplinary Clinical Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н. И. Пирогова; Московский многопрофильный клинический центр «Коммунарка»; Городская клиническая больница № 1 им. Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University) ; "Kommunarka" Moscow Multidisciplinary Clinical Centre; Pirogov City Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>02</day><month>03</month><year>2025</year></pub-date><volume>13</volume><issue>1</issue><fpage>48</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семенов А.П., Юсуфов А.Г., Гуспанов Р.И., Котов С.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Семенов А.П., Юсуфов А.Г., Гуспанов Р.И., Котов С.В.</copyright-holder><copyright-holder xml:lang="en">Semenov A.P., Yusufov A.G., Guspanov R.I., Kotov S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.urovest.ru/jour/article/view/1010">https://www.urovest.ru/jour/article/view/1010</self-uri><abstract><sec><title>Введение</title><p>Введение. Симптомы нижних мочевыводящих путей (СНМП), сексуальные нарушения и психологические расстройства сосуществуют в жизни мужчин старшего возраста. Оценка распространённости аффективных расстройств и сексуальных дисфункций после оперативного лечения гиперплазии предстательной железы имеет важное значение для обеспечения высокого качества жизни пациентов наряду c СНМП.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Провести анализ частоты встречаемости и тяжести аффективных расстройств у больных до и после лазерной энуклеации предстательной железы, а также оценить их связь с СНМП и эректильной функцией.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включены 136 пациентов с гиперплазией простаты, подвергшихся лазерной энуклеации в период 2018 – 2023 гг. Все мужчины вели половую жизнь, эректильная функция, по данным МИЭФ-5, составляла ≥ 11 баллов. Помимо прохождения стандартных методов обследования, все пациенты на предоперационном этапе и через 18 месяцев после хирургии заполняли опросники IPSS, МИЭФ-5 и HADS. На первом этапе исследования изучали распространённость и тяжесть аффективных расстройств до и после оперативного лечения, определяли их связь с СНМП, на втором этапе изучали связь аффективных расстройств с сексуальными нарушениями. Пациенты были разделены на две группы в зависимости от отсутствия или наличия негативного влияния СНМП на качество сексуальной жизни: группа 1 (n = 70) — влияния нет, группа 2 (n = 66) — влияние есть.</p></sec><sec><title>Результаты</title><p>Результаты. Тревожные и депрессивные расстройства различной степени выраженности обнаружены у 48 (35,3%) и 46 (33,8%) пациентов соответственно. Установлено, что тяжесть как тревожных (r = 0,574; p &lt; 0,001), так и депрессивных расстройств до оперативного лечения коррелировала с СНМП (r = 0,590; p &lt; 0,001), однако после оперативного лечения только баллы тревожных расстройств имели корреляцию с СНМП (r = 0,742; p &lt; 0,001), в частности, с симптомами накопления (r = 0,475; p &lt; 0,001). Пациенты группы 2 имели более низкие баллы МИЭФ-5 (18,0 против 21,0 балла; p &lt; 0,001) и чаще отмечали тревожно-депрессивные расстройства до оперативного лечения (45,7 и 44,3% против 22,8 и 22,7%; p &lt; 0,05), при этом после хирургии у них наблюдалось значимое улучшение эректильной функции и аффективного статуса в отличие от пациентов группы 1, у которых баллы МИЭФ-5 и частота встречаемости аффективных расстройств значимо не менялись.</p></sec><sec><title>Заключение</title><p>Заключение. Пациенты преимущественно с ирритативным профилем СНМП и негативным влиянием нарушенного мочеиспускания на сексуальную жизнь более склонны испытывать тревожно-депрессивные расстройства, поэтому при лечении мужчин с СНМП важно оценивать их аффективный статус с целью повышения качества их жизни.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Lower urinary tract symptoms (LUTS), sexual dysfunction and psychological disorders coexist in the lives of older men. Evaluation of the prevalence of mood disorders and sexual dysfunction after surgical treatment is important to ensure a high quality of life for patients with LUTS.</p></sec><sec><title>Objective</title><p>Objective. To analyse the incidence and severity of affective disorders in patients before and after laser enucleation of the prostate and to determine their association with LUTS and erectile dysfunction.</p></sec><sec><title> Materials &amp; methods</title><p> Materials &amp; methods. The study included 136 patients with benign prostatic hyperplasia treated with laser enucleation between 2018 and 2023. All the male participants were sexually active, and their erectile function was assessed at 11 points or higher according to the IIEF-5 scale. In addition to standard examination methods, all patients completed the IPSS, IIEF-5, and HADS questionnaires prior to surgery and 18 months postoperatively. The first stage of the study involved an investigation into the prevalence and severity of affective disorders both before and after surgical intervention, as well as determining their correlation with LUTS. The second stage focused on examining the relationship between affective disorders and sexual dysfunction. Patients were categorized into two groups based on the absence or presence of negative influence of LUTS on their quality of sexual life: group 1 (n = 70) — no influence, group 2 (n = 66) — influence is present.</p></sec><sec><title>Results</title><p>Results. Anxiety and depressive disorders of varying severity were found in 48 (35.3%) and 46 (33.8%) patients, respectively. It was found that the severity of both anxiety (r = 0.574; p &lt; 0.001) and depressive disorders before surgical treatment correlated with LUTS (r = 0.590; p &lt; 0.001), but after surgical treatment only anxiety disorder scores had a correlation with LUTS (r = 0.742; p &lt; 0.001), and with irritative symptoms (r = 0.475; p &lt; 0.001). Group 2 patients had lower IIEF-5 scores (18.0 vs. 21.0 points; p &lt; 0.001) and were more likely to have anxiety and depressive disorders before surgical treatment (45.7 and 44.3% vs. 22.8 and 22.7%; p &lt; 0.05), with significant improvement in erectile function and affective status after surgery, in contrast to group 1 patients, whose IIEF-5 scores and incidence of affective disorders did not change significantly.</p></sec><sec><title>Conclusion</title><p>Conclusion. Patients with a predominantly irritative LUTS profile and a negative impact of urinary disturbances on sexual life are more susceptible to anxiety and depressive disorders. Consequently, evaluating their affective state is essential when treating men with LUTS to enhance their quality of life.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гиперплазия предстательной железы</kwd><kwd>лазерная энуклеация</kwd><kwd>симптомы нижних мочевых путей</kwd><kwd>эректильная дисфункция</kwd><kwd>аффективные расстройства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>benign prostate hyperplasia</kwd><kwd>laser enucleation</kwd><kwd>lower urinary tract symptoms</kwd><kwd>erectile dysfunction</kwd><kwd>affective disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Garraway WM, Collins GN, Lee RJ. High prevalence of benign prostatic hypertrophy in the community. Lancet. 1991;338(8765):469-71. DOI: 10.1016/0140-6736(91)90543-x</mixed-citation><mixed-citation xml:lang="en">Garraway WM, Collins GN, Lee RJ. 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